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Neil A. Whittemore
Researcher at University of Tennessee
Publications - 10
Citations - 391
Neil A. Whittemore is an academic researcher from University of Tennessee. The author has contributed to research in topics: Vitronectin & Aminoglycoside. The author has an hindex of 8, co-authored 10 publications receiving 379 citations. Previous affiliations of Neil A. Whittemore include University of Colorado Boulder.
Papers
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Journal ArticleDOI
Hydrogen-deuterium (H/D) exchange mapping of Abeta 1-40 amyloid fibril secondary structure using nuclear magnetic resonance spectroscopy.
Neil A. Whittemore,Rajesh P. Mishra,Indu Kheterpal,Angela Williams,Ronald Wetzel,Engin H. Serpersu +5 more
TL;DR: The data substantially supports current models for how the Abeta peptide folds when it engages in the amyloid fibril structure, while also addressing some discrepancies between models.
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Discovery of non-carbohydrate inhibitors of aminoglycoside-modifying enzymes
Karen T. Welch,Kristopher G. Virga,Neil A. Whittemore,Can Özen,Edward Wright,Cynthia Lee Brown,Richard E. Lee,Engin H. Serpersu +7 more
TL;DR: These studies yielded the first non-carbohydrate inhibitor N-cyclohexyl-N'-(3-dimethylamino-propyl)-propane-1,3-diamine (Compound G,H) that is competitive with respect to the aminoglycoside binding to the enzyme aminglycoside-2''-nucleotidyltransferase-Ia (ANT2'').
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The Solution Structure of the N-terminal Domain of Human Vitronectin PROXIMAL SITES THAT REGULATE FIBRINOLYSIS AND CELL MIGRATION
TL;DR: The three-dimensional structure of an N-terminal fragment comprising the first 51 amino acids from human plasma vitronectin, the somatomedin B (SMB) domain, has been determined by two-dimensional NMR approaches and reveals the relative orientation of binding sites for cell surface receptors.
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Synthesis and electrochemistry of anthraquinone-oligodeoxynucleotide conjugates.
Neil A. Whittemore,Mullenix An,Inamati Gb,Muthiah Manoharan,Cook Pd,Albert A. Tuinman,David C. Baker,James Q. Chambers +7 more
TL;DR: The synthetic methodology allows the synthesis of ODNs with electroactive tags attached to given locations in the base sequence and the cyclic voltammetric response of the duplexes formed from the AQ-ODNs and their complementary ODN was complicated by the competitive adsorption of the individual ODNs and possibly the Duplex species as well.
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Anthocyanins from wild carrot suspension cultures acylated with supplied carboxylic acids
TL;DR: In this paper, Carrot cells accommodate a wide range of carboxylic acids used to acylate anthocyanins and provide a system for the preparation of Anthocyanin that have a variety of acyl groups attached.