N
Nelson Lee
Researcher at University of Alberta
Publications - 203
Citations - 16069
Nelson Lee is an academic researcher from University of Alberta. The author has contributed to research in topics: Influenza A virus & Viral load. The author has an hindex of 56, co-authored 200 publications receiving 14087 citations. Previous affiliations of Nelson Lee include The Chinese University of Hong Kong & University of Amsterdam.
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Journal ArticleDOI
A Major Outbreak of Severe Acute Respiratory Syndrome in Hong Kong
Nelson Lee,David S.C. Hui,Alan Wu,Paul K.S. Chan,Peter Cameron,Gavin M. Joynt,Anil T. Ahuja,Man Yee Yung,Chi-Bon Leung,Ka Fai To,Siu F. Lui,Cheuk-Chun Szeto,S.C.Sydney Chung,Joseph J.Y. Sung +13 more
TL;DR: SARS is a serious respiratory illness that led to significant morbidity and mortality in this cohort of 138 cases of suspected SARS during a hospital outbreak in Hong Kong.
Journal ArticleDOI
Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome.
Chun K. Wong,C. W. K. Lam,A. K. L. Wu,W. K. Ip,Nelson Lee,I. H. S. Chan,Lydia C.W. Lit,David S.C. Hui,M. H. M. Chan,S. S. C. Chung,Joseph J.Y. Sung +10 more
TL;DR: Together, the elevation of Th1 cytokine IFN‐γ, inflammatory cytokine IL‐1, IL‐6 and IL‐12 and chemokines IL‐8, MCP‐1 and IP‐10 confirmed the activation of Th 1 cell‐mediated immunity and hyperinnate inflammatory response in SARS through the accumulation of monocytes/macrophages and neutrophils.
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Enteric involvement of severe acute respiratory syndrome-associated coronavirus infection.
Wai K. Leung,Ka Fai To,Paul K.S. Chan,Henry Lik-Yuen Chan,Alan K.L. Wu,Nelson Lee,Kwok-Yung Yuen,Joseph J.Y. Sung +7 more
TL;DR: The intestinal tropism of the SARS-CoV has major implications on clinical presentation and viral transmission.
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Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents
Frederick G. Hayden,Sugaya N,Hirotsu N,Nelson Lee,de Jong,Aeron C. Hurt,Ishida T,Sekino H,Yamada K,Simon Portsmouth,Keiko Kawaguchi,Takao Shishido,Arai M,Kenji Tsuchiya,Takeki Uehara,Akira Watanabe +15 more
TL;DR: Single‐dose baloxavir was without evident safety concerns, was superior to placebo in alleviating influenza symptoms, and was superiorto both oseltamivir and placebo in reducing the viral load 1 day after initiation of the trial regimen in patients with uncomplicated influenza.
Journal ArticleDOI
Haematological manifestations in patients with severe acute respiratory syndrome : retrospective analysis
Raymond S.M. Wong,Alan Wu,Ka Fai To,Nelson Lee,Christopher W.K. Lam,Chun K. Wong,Paul K.S. Chan,Margaret H.L. Ng,Ling Yu,David S.C. Hui,John S. Tam,Gregory Cheng,Joseph J.Y. Sung +12 more
TL;DR: Abnormal haematological variables were common among patients with SARS and the depletion of T lymphocyte subsets may be associated with disease activity.