Neville Boden

TL;DR: A generic statistical mechanical model is presented for the self-assembly of chiral rod-like units, such as β-sheet-forming peptides, into helical tapes, which with increasing concentration associate into twisted ribbons, fibrils, and fibers and sheds new light on the factors governing the structures and stability of pathological amyloid fibrs in vivo.

TL;DR: This work describes the construction of oligopeptides, rationally designed or based on segments of native proteins, that aggregate in suitable solvents into long, semi-flexible β-sheet tapes and suggests that it should be possible to engineer a wide range of properties in these gels by appropriate choice of the peptide primary structure.

TL;DR: An important design principle, that stabilization of fibrillar dispersions requires of the order of one unit of net positive or negative charge per peptide molecule, is first demonstrated and then used to design an 11 amino acid peptide whose self-assembly behavior is independent of pH.

TL;DR: In this article, it has been shown that a new class of quasi-one-dimensional conductors can be created by doping discotic liquid crystals with appropriate oxidants, which is characteristic of charge carrier transport by a hopping mechanism.