N
Nicholas A. Kefalides
Researcher at University City Science Center
Publications - 108
Citations - 5234
Nicholas A. Kefalides is an academic researcher from University City Science Center. The author has contributed to research in topics: Basement membrane & Type IV collagen. The author has an hindex of 38, co-authored 108 publications receiving 5182 citations. Previous affiliations of Nicholas A. Kefalides include University of Pennsylvania & Drexel University.
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Book ChapterDOI
Biochemistry and metabolism of basement membranes.
TL;DR: Basement membranes or basal laminae are ubiquitous in the vertebrate and invertebrate world and constitute important structural and functional extracellular matrices and serve as a boundary between cell types or between cell layers and the underlying connective tissue.
Journal ArticleDOI
Characterization of a renal tubular epithelial cell line which secretes the autologous target antigen of autoimmune experimental interstitial nephritis
Thomas P. Haverty,Carolyn J. Kelly,William H. Hines,Peter S. Amenta,Melanie Watanabe,Robert A. Harper,Nicholas A. Kefalides,Eric G. Neilson +7 more
TL;DR: It is suggested that MCT cells provide all the necessary biological parameters for interfacing both as the target of a nephritogenic immune response, and as a potential source for new extracellular matrix which develops as a fibrogenic response to interstitial nephritis.
Journal ArticleDOI
Isolation of a collagen from basement membranes containing three identical α-chains
TL;DR: Chromatographic studies on CM-cellulose of collagens isolated from basement membranes of the glomerulus, lens capsule and Descemet's membrane indicate that the molecule is composed of three identical α -1 chains.
Journal ArticleDOI
Virus infection of endothelial cells.
TL;DR: The results suggest that viral replication within endothelium may be important in the pathogenesis of viral disease of initiation of vessel-wall injury.