N
Nicola Ferri
Researcher at University of Padua
Publications - 212
Citations - 5928
Nicola Ferri is an academic researcher from University of Padua. The author has contributed to research in topics: PCSK9 & Medicine. The author has an hindex of 35, co-authored 175 publications receiving 4692 citations. Previous affiliations of Nicola Ferri include University of Milan & University of Washington.
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Non-lipid-related effects of statins
TL;DR: The present review discusses the current knowledge on the non-lipid-related effects of statins, with a special emphasis on their potential benefits in different diseases, such as atherosclerosis and cancer.
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Direct vascular effects of HMG-CoA reductase inhibitors
Stefano Bellosta,Franco Bernini,Nicola Ferri,P. Quarato,M. Canavesi,Lorenzo Arnaboldi,Remo Fumagalli,Rodolfo Paoletti,Alberto Corsini +8 more
TL;DR: Results suggest that HMG-CoA reductase inhibitors exert a direct antiatherosclerotic effect in the arterial wall, beyond their effects on plasma lipids, that could translate into a more significant prevention of cardiovascular disease.
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Proprotein convertase subtilisin kexin type 9 (PCSK9) secreted by cultured smooth muscle cells reduces macrophages LDLR levels.
Nicola Ferri,G. Tibolla,Angela Pirillo,Francesco Cipollone,Andrea Mezzetti,Stefano Pacia,Alberto Corsini,Alberico L. Catapano +7 more
TL;DR: Data indicate that PCSK9 secreted by human SMCs is functionally active and capable of reducing LDLR expression in macrophages, suggesting a possible direct role for this protein in foam cell formation and atherogenesis.
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Thematic Review Series: The Immune System and Atherogenesis. Cytokines affecting endothelial and smooth muscle cells in vascular disease
TL;DR: This review summarizes in vivo studies that have characterized endothelial- and smooth muscle-specific effects of altering cytokine signaling in vascular disease and underscores the need to delineate the critical genes and specific cellular functions regulated by individual cytokine signaled pathways.
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Drug attrition during pre-clinical and clinical development: Understanding and managing drug-induced cardiotoxicity
TL;DR: In this paper, the authors summarized the clinical manifestations of drug-induced cardiotoxicity by various cancer chemotherapies and novel drugs for the treatment of other diseases and presented guidelines for the management of patients exposed to drugs with cardiotoxic potential.