N
Nicola J. Porter
Researcher at University of Edinburgh
Publications - 2
Citations - 37
Nicola J. Porter is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Regeneration (biology) & Chemistry. The author has an hindex of 1, co-authored 2 publications receiving 6 citations.
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CRISPR gRNA phenotypic screening in zebrafish reveals pro-regenerative genes in spinal cord injury
Marcus Keatinge,Themistoklis M. Tsarouchas,Tahimina Munir,Nicola J. Porter,Juan Larraz,Davide Gianni,Hui-Hsin Tsai,Catherina G. Becker,David A. Lyons,Thomas Becker +9 more
TL;DR: In this article, a rapid in-vivo phenotypic screen for macrophage-related genes that promote regeneration after spinal injury was conducted, using acute injection of synthetic RNA Oligo CRISPR guide RNAs that were pre-screened for high activity in vivo.
Journal ArticleDOI
Truly-Biocompatible Gold Catalysis Enables Vivo-Orthogonal Intra-CNS Release of Anxiolytics.
M. Carmen Ortega-Liebana,Nicola J. Porter,Catherine Adam,Teresa Valero,Lloyd Hamilton,Dirk Sieger,Catherina G. Becker,Catherina G. Becker,Asier Unciti-Broceta +8 more
TL;DR: In this article, the authors report the development of a truly catalytic Au-polymer composite by assembling ultrasmall Au-nanoparticles at the protein-repelling outer layer of a copolymer scaffold via electrostatic loading, showing their capacity to uncage the anxiolytic agent fluoxetine at the central nervous system of developing zebrafish, influencing their swim pattern.