N
Nicola Pozzi
Researcher at Saint Louis University
Publications - 76
Citations - 1575
Nicola Pozzi is an academic researcher from Saint Louis University. The author has contributed to research in topics: Thrombin & Medicine. The author has an hindex of 21, co-authored 66 publications receiving 1210 citations. Previous affiliations of Nicola Pozzi include University of Padua.
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Journal ArticleDOI
Anti-Phospholipid Antibodies in COVID-19 Are Different From Those Detectable in the Anti-Phospholipid Syndrome.
Maria Orietta Borghi,Asmaa Beltagy,Emirena Garrafa,Daniele Curreli,Germana Cecchini,Caterina Bodio,Claudia Grossi,Simonetta Blengino,Angela Tincani,Franco Franceschini,Laura Andreoli,Maria Grazia Lazzaroni,Silvia Piantoni,Stefania Masneri,Francesca Crisafulli,Duilio Brugnoni,Maria Lorenza Muiesan,Massimo Salvetti,Gianfranco Parati,Erminio Torresani,Michael Mahler,Francesca Heilbron,Francesca Pregnolato,Martino F. Pengo,Francesco Tedesco,Nicola Pozzi,Pier Luigi Meroni +26 more
TL;DR: APL in COVID-19 patients are mainly directed against β2GPI but display an epitope specificity different from antibodies in antiphospholipid syndrome, which shows a low prevalence and is not associated with major thrombotic events.
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Essential role of conformational selection in ligand binding.
TL;DR: In this article, it was shown that induced fit is always sufficient and often necessary to account for the relaxation kinetics of ligand binding to a biological macromolecule and is therefore an essential component of any binding mechanism.
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Conformational selection in trypsin-like proteases
TL;DR: Analysis of the structural database confirms existence of the E* and E forms and vouches for the allosteric nature of the trypsin fold.
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Endocrine Disruption of Androgenic Activity by Perfluoroalkyl Substances: Clinical and Experimental Evidence
Andrea Di Nisio,Iva Sabovic,Umberto Valente,Simone Tescari,Maria Santa Rocca,Diego Guidolin,Stefano Dall'Acqua,Laura Acquasaliente,Nicola Pozzi,Mario Plebani,Andrea Garolla,Carlo Foresta +11 more
TL;DR: It is found that increased levels of PFCs in plasma and seminal fluid positively correlate with circulating testosterone (T) and with a reduction of semen quality, testicular volume, penile length, and anogenital distance.
Journal ArticleDOI
Antibodies to Domain I of β2Glycoprotein I are in close relation to patients risk categories in Antiphospholipid Syndrome (APS)
Alessandra Banzato,Nicola Pozzi,Roberta Frasson,V. De Filippis,Amelia Ruffatti,E. Bison,Seena Jose Padayattil,Gentian Denas,Vittorio Pengo +8 more
TL;DR: High risk patients with APS and triple laboratory positivity as compared with double and single positivity patients have significantly higher titre of anti-DmI antibodies as evaluated by an inhibition test.