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Nicole J. De Nisco
Researcher at University of Texas at Dallas
Publications - 51
Citations - 879
Nicole J. De Nisco is an academic researcher from University of Texas at Dallas. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 11, co-authored 26 publications receiving 588 citations. Previous affiliations of Nicole J. De Nisco include Massachusetts Institute of Technology & University of Texas Southwestern Medical Center.
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Host plant peptides elicit a transcriptional response to control the Sinorhizobium meliloti cell cycle during symbiosis
Jon Penterman,Ryan Abo,Nicole J. De Nisco,Markus F. F. Arnold,Renato Longhi,Matteo Zanda,Graham C. Walker +6 more
TL;DR: This study provides insights into how host peptides cause differentiation of S. meliloti during symbiosis through the production of defensin-like peptides called “nodule-specific cysteine-rich” (NCR) peptides.
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Advances in Understanding the Human Urinary Microbiome and Its Potential Role in Urinary Tract Infection
Michael L. Neugent,Neha V. Hulyalkar,Vivian H. Nguyen,Philippe E. Zimmern,Nicole J. De Nisco +4 more
TL;DR: Future diagnostic, prognostic, and therapeutic options for the management of UTI may soon incorporate efforts to measure, restore, and/or preserve the native, healthy ecology of the urinary microbiomes.
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Cell Cycle Control by the Master Regulator CtrA in Sinorhizobium meliloti
Francesco Pini,Nicole J. De Nisco,Lorenzo Ferri,Jon Penterman,Antonella Fioravanti,Matteo Brilli,Alessio Mengoni,Marco Bazzicalupo,Patrick H. Viollier,Graham C. Walker,Emanuele G. Biondi +10 more
TL;DR: In this paper, the authors investigated the regulation and function of CtrA in S. meliloti and found that depletion of the master regulator can cause cell elongation, branching and genome amplification.
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Global analysis of cell cycle gene expression of the legume symbiont Sinorhizobium meliloti
TL;DR: A robust method for synchronizing cell growth that enabled global analysis of S. meliloti cell cycle-regulated gene expression is described and suggests that the CtrA cell cycle regulatory network may control functions of central importance to the specific lifestyles of α-proteobacteria.
Journal ArticleDOI
Direct Detection of Tissue-Resident Bacteria and Chronic Inflammation in the Bladder Wall of Postmenopausal Women with Recurrent Urinary Tract Infection.
Nicole J. De Nisco,Michael L. Neugent,Jason Mull,Luming Chen,Amy Kuprasertkul,Marcela de Souza Santos,Kelli L. Palmer,Philippe E. Zimmern,Kim Orth +8 more
TL;DR: Analysis of urine and bladder biopsy samples from postmenopausal women undergoing cystoscopy with fulguration of trigonitis in the advanced management of antibiotic-refractory RUTI provides conclusive evidence that bacteria invade the human urothelium and suggests that diverse bacterial species and the adaptive immune response play important roles in RUTi in humans.