N
Niels Peek
Researcher at University of Manchester
Publications - 275
Citations - 5832
Niels Peek is an academic researcher from University of Manchester. The author has contributed to research in topics: Medicine & Health care. The author has an hindex of 37, co-authored 238 publications receiving 4184 citations. Previous affiliations of Niels Peek include RMIT University & University of Amsterdam.
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External validation of prognostic models for critically ill patients required substantial sample sizes
TL;DR: Substantial sample sizes are required for performance assessment and model comparison in external validation of prognostic models for outcome at intensive care units (ICUs) andCalibration statistics and significance tests should not be used in these settings.
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The effect of computerized decision support on barriers to guideline implementation: A qualitative study in outpatient cardiac rehabilitation
Rick Goud,Mariëtte M. van Engen-Verheul,Nicolette F. de Keizer,Roland Bal,Arie Hasman,Irene M. Hellemans,Niels Peek +6 more
TL;DR: The results suggest that computerized decision support can improve guideline implementation by increasing the knowledge of preferred practice, by reducing inertia to previous practice, and by reducing guideline complexity.
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Prognostic Bayesian networks
TL;DR: The prognostic Bayesian network (PBN) is presented as a new type of prognostic model that builds on theBayesian network methodology, and implements a dynamic, process-oriented view on prognosis.
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Technical Challenges for Big Data in Biomedicine and Health: Data Sources, Infrastructure, and Analytics
TL;DR: The major challenge for the near future is to transform analytical methods that are used in the biomedical and health domain, to fit the distributed storage and processing model that is required to handle big data, while ensuring confidentiality of the data being analyzed.
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Trends in admission prevalence, illness severity and survival of haematological patients treated in Dutch intensive care units
Maarten van Vliet,Ilona W. M. Verburg,Mark van den Boogaard,Nicolette F. de Keizer,Niels Peek,Nicole M. A. Blijlevens,Peter Pickkers +6 more
TL;DR: While mortality is significantly higher in this group of medical ICU patients than in subgroups of non-haematological ones, the former show a similar decrease in raw and risk-adjusted mortality rate over time, while leukocytopenia is not a predictor of mortality.