Niels Rahe-Meyer

TL;DR: The perioperative endocrine stress response was attenuated in patients supplemented with continuous remifentanil infusion as compared to intermittent fentanyl, and cardiopulmonary bypass times and aortic cross‐clamp times were longer in the fentanyl group, which may to some extent account for the differences.

TL;DR: A new technical solution for valid, reproducible in vivo force measurements on every possible point of the stretching curve is introduced and it should be possible to study the muscle contraction in vivo to the same level of accuracy as is achieved in tests with in vitro organ preparations.

TL;DR: FIBTEM-guided intraoperative hemostatic therapy with fibrinogen concentrate is more effective than placebo in controlling coagulopathic bleeding during major aortic replacement surgery and is more rapid than--and at least as effective as--2 cycles of fresh-frozen plasma/platelets.

TL;DR: Fibrinogen concentrate provided specific, significant, short-lived increases in plasma fibr inogen and fibrin-based clot firmness after aortic surgery.

TL;DR: Sugammadex produced limited, transient (<1 h) increases in activated partial thromboplastin time and prothrombin time but was not associated with increased risk of bleeding versus usual care, and no cases of anaphylaxis.