Nikhil Kapoor

TL;DR: In this paper, the authors investigated the profile and survival patterns of patients with severe aortic stenosis who did not have AVR and found that the Aortic valve replacement (AVR) is not offered to many patients for various reasons, including advanced age, low LV ejection fraction, heart failure, elevated serum creatinine level, severe mitral regurgitation, and pulmonary hypertension.

TL;DR: AVR appears to improve survival of elderly patients with severe calcific aortic stenosis and should be strongly considered in the absence of other major comorbidities.

TL;DR: The observational data indicate that the natural history of asymptomatic AS is not benign and that survival is dramatically improved by AVR, and the benefit of AVR was further supported by sensitivity and propensity score analyses.

TL;DR: Aortic valve replacement in patients with severe pulmonary hypertension secondary to severe AS is associated with a huge survival benefit and AVR should be considered urgently in severe AS patients withsevere pulmonary hypertension.

TL;DR: S Severity of aortic stenosis, left ventricular dysfunction, and mitral regurgitation are risk factors for the genesis of pulmonary hypertension and statins may potentially be protective in patients with severe aorta stenosis.