Journal ArticleDOI
Clinical Profile and Natural History of 453 Nonsurgically Managed Patients With Severe Aortic Stenosis
TLDR
In this paper, the authors investigated the profile and survival patterns of patients with severe aortic stenosis who did not have AVR and found that the Aortic valve replacement (AVR) is not offered to many patients for various reasons, including advanced age, low LV ejection fraction, heart failure, elevated serum creatinine level, severe mitral regurgitation, and pulmonary hypertension.About:
This article is published in The Annals of Thoracic Surgery.The article was published on 2006-12-01. It has received 479 citations till now. The article focuses on the topics: Aortic valve stenosis & Ejection fraction.read more
Citations
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Journal ArticleDOI
Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery
Martin B. Leon,Craig R. Smith,Michael J. Mack,D. Craig Miller,Jeffrey W. Moses,Lars G. Svensson,E. Murat Tuzcu,John G. Webb,Gregory P. Fontana,Raj Makkar,David L. Brown,Peter C. Block,Robert A. Guyton,Augusto D. Pichard,Joseph E. Bavaria,Howard C. Herrmann,Pamela S. Douglas,John L. Petersen,Jodi J. Akin,William N. Anderson,Duolao Wang,Stuart J. Pocock +21 more
TL;DR: In patients with severe aortic stenosis who were not suitable candidates for surgery, TAVI, as compared with standard therapy, significantly reduced the rates of death from any cause, the composite end point of deathFrom any cause or repeat hospitalization, and cardiac symptoms, despite the higher incidence of major strokes and major vascular events.
Journal ArticleDOI
Transcatheter versus Surgical Aortic-Valve Replacement in High-Risk Patients
Craig R. Smith,Martin B. Leon,Michael J. Mack,D. Craig Miller,Jeffrey W. Moses,Lars G. Svensson,E. Murat Tuzcu,John G. Webb,Gregory P. Fontana,Raj Makkar,Mathew R. Williams,Todd M. Dewey,Samir R. Kapadia,Vasilis Babaliaros,Vinod H. Thourani,Paul J. Corso,Augusto D. Pichard,Joseph E. Bavaria,Howard C. Herrmann,Jodi J. Akin,William N. Anderson,Duolao Wang,Stuart J. Pocock +22 more
TL;DR: In high-risk patients with severe aortic stenosis, transcatheter and surgical procedures for aorti-valve replacement were associated with similar rates of survival at 1 year, although there were important differences in periprocedural risks.
Journal ArticleDOI
Two-Year Outcomes after Transcatheter or Surgical Aortic-Valve Replacement
Susheel Kodali,Mathew R. Williams,Craig R. Smith,Lars G. Svensson,John G. Webb,Raj Makkar,Gregory P. Fontana,Todd M. Dewey,Vinod H. Thourani,Augusto D. Pichard,Michael P. Fischbein,Wilson Y. Szeto,Scott Lim,Kevin L. Greason,Paul S. Teirstein,S. Chris Malaisrie,Pamela S. Douglas,Rebecca T. Hahn,Brian Whisenant,Alan Zajarias,Duolao Wang,Jodi J. Akin,William N. Anderson,Martin B. Leon,Trial Investigators +24 more
TL;DR: A 2-year follow-up of patients in the PARTNER trial supports TAVR as an alternative to surgery in high-risk patients, but paravalvular regurgitation was more frequent after T AVR and was associated with increased late mortality.
Journal ArticleDOI
Standardized Endpoint Definitions for Transcatheter Aortic Valve Implantation Clinical Trials : A Consensus Report From the Valve Academic Research Consortium
Martin B. Leon,Nicolo Piazza,Eugenia Nikolsky,Eugene H. Blackstone,Donald E. Cutlip,Arie Pieter Kappetein,Mitchell W. Krucoff,Michael J. Mack,Roxana Mehran,Craig Miller,Marie-Angèle Morel,John L. Petersen,Jeffrey J. Popma,Johanna J.M. Takkenberg,Alec Vahanian,Gerrit-Anne van Es,Pascal Vranckx,John G. Webb,Stephan Windecker,Patrick W. Serruys +19 more
TL;DR: Although consensus criteria will invariably include certain arbitrary features, an organized multidisciplinary process to develop specific definitions for TAVI clinical research should provide consistency across studies that can facilitate the evaluation of this new important catheter-based therapy.
Journal ArticleDOI
Percutaneous transarterial aortic valve replacement in selected high-risk patients with aortic stenosis.
John G. Webb,Sanjeevan Pasupati,Karin H. Humphries,Christopher R. Thompson,Lukas Altwegg,Robert Moss,Ajay Sinhal,Ronald G. Carere,Brad Munt,Donald R. Ricci,Jian Ye,Anson Cheung,Sam V. Lichtenstein +12 more
TL;DR: Percutaneous valve replacement may be an alternative to conventional open heart surgery in selected high-risk patients with severe symptomatic aortic stenosis in whom there was a consensus that the risks of conventional openheart surgery were very high.
References
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Journal ArticleDOI
ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
Robert O. Bonow,Blase A. Carabello,Kanu Chatterjee,Antonio C. de Leon,David P. Faxon,Michael D. Freed,William H. Gaasch,Bruce W. Lytle,Rick A. Nishimura,Patrick T. O'Gara,Robert A. O'Rourke,Catherine M Otto,Pravin M. Shah,Jack S. Shanewise +13 more
TL;DR: It is important that the medical profession play a significant role in critically evaluating the use of diagnostic procedures and therapies as they are introduced in the detection, management, and management of diseases.
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Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms.
Nelson B. Schiller,P. M. Shah,Michael H. Crawford,Anthony N. DeMaria,Richard B. Devereux,Harvey Feigenbaum,H. Gutgesell,Nathaniel Reichek,David J. Sahn,Ingela Schnittger +9 more
TL;DR: It is the opinion that current technology justifies the clinical use of the quantitative two-dimensional methods described in this article and the routine reporting of left ventricular ejection fraction, diastolic volume, mass, and wall motion score.
Journal ArticleDOI
The logistic EuroSCORE
TL;DR: Dear Sir, The European System for Cardiac Operative Risk Evaluation (EuroSCORE) identifies a number of risk factors which help to predict mortality from cardiac surgery.
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The natural history of aortic valve stenosis.
D. Horstkotte,F. Loogen +1 more
TL;DR: Despite different aetiologies, acquired aortic stenosis is a self-maintaining, slowly progressive process with good long-term prognosis, and there was clinical progression within 10 years of the initial diagnosis in only 12% of patients.
Journal ArticleDOI
Guidelines for the management of patients with valvular heart disease: Executive summary: A report of the American college of cardiology/American heart association task force on practice guidelines (Committee on management of patients with valvular heart disease)
Robert O. Bonow,Blase A. Carabello,Antonio C. de Leon,L. Henry Edmunds,Bradley J. Fedderly,Michael D. Freed,William H. Gaasch,Charles R. McKay,Rick A. Nishimura,Patrick T. O'Gara,Robert A. O'Rourke,Shahbudin H. Rahimtoola,James L. Ritchie,Melvin D. Cheitlin,Kim A. Eagle,Timothy J. Gardner,Arthur Garson,Raymond J. Gibbons,Richard O. Russell,Thomas J. Ryan,Sidney C. Smith +20 more
TL;DR: A report of the 2008 Focused Update Incorporated Into the ACC/AHA 2006 Guidelines for the Valvular Heart Disease : A Report of the2008 Focused update Incorporated into the ACC and AHA 2006 guidelines for management of patients with valvular heart disease.
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