N
Nilklas Schultz
Researcher at Stockholm University
Publications - 1
Citations - 4262
Nilklas Schultz is an academic researcher from Stockholm University. The author has contributed to research in topics: Homologous recombination & DNA repair. The author has an hindex of 1, co-authored 1 publications receiving 3709 citations.
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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
Helen E. Bryant,Nilklas Schultz,Huw D. Thomas,Kayan M. Parker,Dan Flower,Elena Lopez,Suzanne Kyle,Mark Meuth,Nicola J. Curtin,Thomas Helleday,Thomas Helleday +10 more
TL;DR: It is proposed that, in the absence of PARP1, spontaneous single-strand breaks collapse replication forks and trigger homologous recombination for repair and exploited in order to kill BRCA2-deficient tumours by PARP inhibition alone.