Nils Jakob Vest Hansen

TL;DR: An 800-million-member DNA-encoded library in which small molecules are covalently attached to an encoding oligonucleotide is reported, assembled by a combination of chemical and enzymatic synthesis, and interrogated by affinity selection.

TL;DR: In this article, a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag was proposed. But this method is not suitable for the use of binary codes.

TL;DR: In this article, a method for identifying a compound of interest by screening libraries of molecules which include an encoding oligonucleotide tag was proposed, which was used to identify a compound.

TL;DR: In the version of this article initially published, the IC50 values in the table in Figure 3c were listed as nM instead of μM, and the error has been corrected in the HTML and PDF versions of the article.

TL;DR: In this paper, a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag, and identifying compounds which bind to said biological target is presented. But this method is limited to the case of binary codes.