Ning He

TL;DR: This study indicated that artesunate induces autophagy dependent apoptosis through upregulating ROS and activating AMPK-mTOR-ULK1 pathway in human bladder cancer cells.

TL;DR: It is demonstrated that circRIMS1 promotes tumor growth, migration, and invasion through the miR-433-3p/CCAR1 regulatory axis, representing a potential therapeutic target and biomarker in bladder cancer.

TL;DR: In this article, the authors showed that BA exposure significantly suppressed viability, proliferation, and migration of EJ and T24 human bladder cancer cells, which reflected caspase 3-mediated apoptosis and could be attenuated or abolished by inhibiting ROS production with Nacetyl-L-cysteine, inhibiting autophagy with chloroquine, or silencing ATG7 with targeted siRNA.

TL;DR: In this article, the underlying molecular mechanisms of the TAZ-induced biological effects in bladder cancer were discovered, and a novel positive feedback loop between TAZ and miR-942-3p was identified.

TL;DR: In this paper, the authors selected circPPP1CB as a study object by circRNA sequencing and quantitative real-time PCR (qRT-PCR) validation in human bladder cancer (BC).