N
Ning Wang
Researcher at University of Illinois at Urbana–Champaign
Publications - 186
Citations - 22738
Ning Wang is an academic researcher from University of Illinois at Urbana–Champaign. The author has contributed to research in topics: Cytoskeleton & Mechanotransduction. The author has an hindex of 69, co-authored 166 publications receiving 20733 citations. Previous affiliations of Ning Wang include University of Kansas & University of Cologne.
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Journal ArticleDOI
Mechanotransduction across the cell surface and through the cytoskeleton
TL;DR: The results suggest that integrins act as mechanoreceptors and transmit mechanical signals to the cytoskeleton, which may be mediated simultaneously at multiple locations inside the cell through force-induced rearrangements within a tensionally integrated cytos skeleton.
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Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus
TL;DR: The molecular mechanisms by which forces might act at a distance to induce mechanochemical conversion in the nucleus and alter gene activities are explored.
Journal ArticleDOI
Mechanical behavior in living cells consistent with the tensegrity model
Ning Wang,Keiji Naruse,Dimitrije Stamenović,Jeffrey J. Fredberg,Srboljub M. Mijailovich,Iva Marija Tolić-Norrelykke,Thomas R. Polte,Robert Mannix,Donald E. Ingber +8 more
TL;DR: Findings suggest that tensegrity represents a unified model of cell mechanics that may help to explain how mechanical behaviors emerge through collective interactions among different cytoskeletal filaments and extracellular adhesions in living cells.
Journal ArticleDOI
Mechanotransduction across the cell surface and through the cytoskeleton
TL;DR: The results suggest that integrins act as mechanoreceptors and transmit mechanical signals to the cytoskeleton, which may be mediated simultaneously at multiple locations inside the cell through force-induced rearrangements within a tensionally integrated cytos skeleton.
Journal ArticleDOI
Cell prestress. I. Stiffness and prestress are closely associated in adherent contractile cells
Ning Wang,Iva Marija Tolić-Norrelykke,Jianxin Chen,Srboljub M. Mijailovich,James P. Butler,Jeffrey J. Fredberg,Dimitrije Stamenović +6 more
TL;DR: Data establish a strong association between stiffness of HASM cells and the level of tensile stress within the cytoskeleton, a hallmark of systems that secure shape stability mainly through the prestress.