Showing papers by "Noam A. Cohen published in 1996"

TL;DR: This work reports that two inwardly rectifying K+ channels, Kir 2.1 and 2.3, bind to PSD-95, a cytoskeletal protein of postsynaptic densities that clusters NMDA receptors and voltage-dependent K-dependent channels.

TL;DR: The molecular basis of G-protein inhibition of inward rectifier K+ currents was examined by co-expression of Gproteins and cloned Kir2 channel subunits in Xenopus oocytes to demonstrate suppression of Kir2.3 currents resulting from a direct protein-protein interaction between the channel and G- protein βγ subunits.