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Nobuko Yamashita
Researcher at Okayama University
Publications - 21
Citations - 407
Nobuko Yamashita is an academic researcher from Okayama University. The author has contributed to research in topics: Virus & Influenza A virus. The author has an hindex of 10, co-authored 20 publications receiving 371 citations.
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Journal ArticleDOI
Activation of Akt is associated with poor prognosis and chemotherapeutic resistance in pediatric B-precursor acute lymphoblastic leukemia.
Naoto Morishita,Hirokazu Tsukahara,Kosuke Chayama,Toshiaki Ishida,Kana Washio,Takako Miyamura,Nobuko Yamashita,Megumi Oda,Tsuneo Morishima +8 more
TL;DR: This study was undertaken to explore the clinical relevance and molecular mechanisms underlying the activation of Akt (i.e., phosphorylated Akt, P‐Akt) in pediatric B‐pre ALL.
Journal ArticleDOI
Prognostic factors in influenza-associated encephalopathy.
Takashi Nagao,Tsuneo Morishima,Hiroshi Kimura,S Yokota,Nobuko Yamashita,Takashi Ichiyama,Mana Kurihara,Chiaki Miyazaki,Nobuhiko Okabe +8 more
TL;DR: A nationwide study in Japan identified patients who had factors associated with a poor prognosis, and these findings might be clinically useful for the management of this illness.
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Increase of tumor necrosis factor-α in the blood induces early activation of matrix metalloproteinase-9 in the brain
Mitsuru Tsuge,Kozo Yasui,Takashi Ichiyawa,Yukie Saito,Yoshiharu Nagaoka,Masato Yashiro,Nobuko Yamashita,Tsuneo Morishima +7 more
TL;DR: It is suggested that early activation of MMP‐9 in the brain may contribute to an early onset of neurological disorders and brain edema prior to multiple organ failure in those inflammatory diseases associated with highly increased concentrations of TNF‐α in the blood, such as sepsis, burns, trauma and influenza‐associated encephalopathy.
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Management of Severe Neutropenia With Cyclosporin During Initial Treatment of Epstein-Barr Virus-Related Hemophagocytic Lymphohistiocytosis
Shinsaku Imashuku,Shigeyoshi Hibi,Kikuko Kuriyama,Yasuhiro Tabata,Tetsuo Hashida,Asayuki Iwai,Masahiko Kato,Nobuko Yamashita,Megumi Oda,Masashi Uchida,Naoko Kinugawa,Machiko Sawada,Mutsuko Konno +12 more
TL;DR: Improved neutrophil recovery as a result of CSA treatment makes it possible to continue immunochemotherapy safely and obtain improved patient outcomes.
Journal Article
HHV-6 and seizures.
TL;DR: Human herpes virus-6 (HHV-6) is a ubiquitous virus, but one that can induce various neurological diseases, including limbic encephalitis and temporal lobe epilepsy, which can occur in both immunocompromised and Immunocompetent hosts.