N
Noppawan Rangkasenee
Researcher at Mahidol University
Publications - 2
Citations - 89
Noppawan Rangkasenee is an academic researcher from Mahidol University. The author has contributed to research in topics: Vacuole & Cancer. The author has an hindex of 2, co-authored 2 publications receiving 26 citations.
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Journal ArticleDOI
High-content screening of Thai medicinal plants reveals Boesenbergia rotunda extract and its component Panduratin A as anti-SARS-CoV-2 agents.
Phongthon Kanjanasirirat,Ampa Suksatu,Suwimon Manopwisedjaroen,Bamroong Munyoo,Patoomratana Tuchinda,Kedchin Jearawuttanakul,Sawinee Seemakhan,Sitthivut Charoensutthivarakul,Patompon Wongtrakoongate,Noppawan Rangkasenee,Supaporn Pitiporn,Neti Waranuch,Napason Chabang,Phisit Khemawoot,Khanit Sa-ngiamsuntorn,Yongyut Pewkliang,Piyanoot Thongsri,Somchai Chutipongtanate,Suradej Hongeng,Suparerk Borwornpinyo,Arunee Thitithanyanont +20 more
TL;DR: It is demonstrated, for the first time, that panduratin A exerts the inhibitory effect against SARS-CoV-2 infection at both pre-entry and post-infection phases.
Journal ArticleDOI
A novel potent autophagy inhibitor ECDD-S27 targets vacuolar ATPase and inhibits cancer cell survival.
Jiraporn Paha,Phongthon Kanjanasirirat,Bamroong Munyoo,Patoomratana Tuchinda,Naravut Suvannang,Chanin Nantasenamat,Kanokthip Boonyarattanakalin,Prasat Kittakoop,Sirawit Srikor,Gunganist Kongklad,Noppawan Rangkasenee,Suradej Hongeng,Pongsak Utaisincharoen,Suparerk Borwornpinyo,Marisa Ponpuak +14 more
TL;DR: Data indicated that ECDD-S27 retards the autophagy pathway by targeting the V-ATPase and inhibits cancer cell survival, and the observed antitumor activity without cytotoxicity to normal cells suggests the therapeutic potential warranting further studies on lead optimization of the compound for cancer treatment.