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Showing papers by "Norton D. Zinder published in 1966"



Journal ArticleDOI
TL;DR: These results provide support for the existence of a phage-induced enzyme (enzyme I) which converts single-stranded viral RNA into a double-Stranded form late in infection.

109 citations


Journal ArticleDOI
01 Mar 1966-Virology
TL;DR: Temperature-sensitive mutants of phage f2 have been isolated and classified into three groups by physiological criteria, and these mutants can be related to a series of amber mutants of f2.

82 citations


Journal ArticleDOI
15 Apr 1966-Science
TL;DR: A model is presented for the replication of phage RNA on the basis of events occurring after infection of bacteria with wild-type and a temperature-sensitive mutant phage, which indicates that there are two enzymatic activities necessary to replicatephage RNA.
Abstract: Events occurring after infection of bacteria with wild-type and a temperature-sensitive mutant phage indicate that there are two enzymatic activities necessary to replicate phage RNA. One converts single strands into double strands, while the other uses double strands to svnthesize viral RNA. The mutant is deficient in the first activity, probably because the mutation is in the gene specifying the requisite enzyme. On the basis of these and other results, a model is presented for the replication of phage RNA.

73 citations


Journal ArticleDOI
TL;DR: In this article, Amino-and carboxyl-terminal analyses were performed on the protein and the peptides, and the tryptic peptides which occupy the terminal positions in the protein were identified.

38 citations