O
O. Howard Frazier
Researcher at The Texas Heart Institute
Publications - 79
Citations - 8310
O. Howard Frazier is an academic researcher from The Texas Heart Institute. The author has contributed to research in topics: Ventricular assist device & Heart failure. The author has an hindex of 36, co-authored 79 publications receiving 7758 citations. Previous affiliations of O. Howard Frazier include University Medical Center New Orleans & Baylor College of Medicine.
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Journal ArticleDOI
Advanced Heart Failure Treated with Continuous-Flow Left Ventricular Assist Device
Mark S. Slaughter,Joseph G. Rogers,Carmelo A. Milano,Stuart D. Russell,John V. Conte,David S. Feldman,Benjamin Sun,Antone Tatooles,Reynolds M. Delgado,James W. Long,Thomas C. Wozniak,Waqas Ghumman,David J. Farrar,O. Howard Frazier +13 more
TL;DR: Treatment with a continuous-flow left ventricular assist device in patients with advanced heart failure significantly improved the probability of survival free from stroke and device failure at 2 years as compared with a pulsatile device.
Journal ArticleDOI
Extended mechanical circulatory support with a continuous-flow rotary left ventricular assist device.
Francis D. Pagani,Leslie W. Miller,Stuart D. Russell,Keith D. Aaronson,Ranjit John,Andrew J. Boyle,John V. Conte,Roberta C. Bogaev,Thomas E. MacGillivray,Yoshifumi Naka,Donna Mancini,H. Todd Massey,Leway Chen,Charles T. Klodell,Juan M. Aranda,Nader Moazami,Gregory A. Ewald,David J. Farrar,O. Howard Frazier +18 more
TL;DR: A continuous-flow LVAD provides effective hemodynamic support for at least 18 months in patients awaiting transplantation, with improved functional status and quality of life.
Journal ArticleDOI
HeartWare ventricular assist system for bridge to transplant: combined results of the bridge to transplant and continued access protocol trial.
Mark S. Slaughter,Francis D. Pagani,Edwin C. McGee,Emma J. Birks,William Cotts,Igor D. Gregoric,O. Howard Frazier,T.B. Icenogle,Samer S. Najjar,Steven W. Boyce,Michael A. Acker,Ranjit John,David R. Hathaway,Kevin B. Najarian,Keith D. Aaronson +14 more
TL;DR: The use of the HeartWare pump as a bridge to transplant continues to demonstrate a high 180-day survival rate despite a low rate of transplant and quality of life scores improved significantly, and adverse event rates remain low.
Journal ArticleDOI
Transmyocardial laser revascularization: Results of a multicenter trial with transmyocardial laser revascularization used as sole therapy for end-stage coronary artery disease
Keith A. Horvath,Lawrence H. Cohn,Denton A. Cooley,John R. Crew,O. Howard Frazier,Bartley P. Griffith,Kamuran A. Kadipasaoglu,Allan M. Lansing,Finn Mannting,Robert March,Mahmood R. Mirhoseini,Craig Smith +11 more
TL;DR: These combined results indicate that transmyocardial laser revascularization provides angina relief, decreases hospital admissions, and improves perfusion in patients with severe coronary artery disease.
Journal ArticleDOI
Low thromboembolism and pump thrombosis with the HeartMate II left ventricular assist device: analysis of outpatient anti-coagulation.
Andrew J. Boyle,Stuart D. Russell,Jeffrey J. Teuteberg,Mark S. Slaughter,Nader Moazami,Francis D. Pagani,O. Howard Frazier,Gerald Heatley,David J. Farrar,Ranjit John +9 more
TL;DR: The rate of thromboembolism during long-term outpatient support with the HeartMate II is low and an appropriate target INR is 1.5 to 2.5 in addition to aspirin therapy.