O
Olivier Saut
Researcher at University of Bordeaux
Publications - 56
Citations - 1143
Olivier Saut is an academic researcher from University of Bordeaux. The author has contributed to research in topics: Population & Partial differential equation. The author has an hindex of 16, co-authored 56 publications receiving 947 citations. Previous affiliations of Olivier Saut include French Institute for Research in Computer Science and Automation & Paul Sabatier University.
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A multiscale mathematical model of avascular tumor growth to investigate the therapeutic benefit of anti-invasive agents.
Benjamin Ribba,Olivier Saut,Thierry Colin,Didier Bresch,Emmanuel Grenier,Jean-Pierre Boissel +5 more
TL;DR: A mechanistically based model is developed which integrates cell cycle regulation and macroscopic tumor dynamics and may aid in evaluating the efficacy of anti-metastatic therapies, thus benefiting the design of prospective clinical trials.
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A pharmacologically based multiscale mathematical model of angiogenesis and its use in investigating the efficacy of a new cancer treatment strategy.
Frédérique Billy,Benjamin Ribba,Olivier Saut,Hélène Morre-Trouilhet,Thierry Colin,Didier Bresch,Jean-Pierre Boissel,Emmanuel Grenier,Jean-Pierre Flandrois +8 more
TL;DR: A multiscale mathematical model of angiogenesis and tumor growth is developed and it is shown that there is a critical treatment dose below which increasing the duration of treatment leads to a loss of efficacy.
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Computational Modeling of Solid Tumor Growth: The Avascular Stage
TL;DR: A multiscale model using PDEs to describe the evolution of the tumor cell densities is used and constitutes now the basis of a numerical platform for tumor growth simulations.
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T2 -based MRI Delta-radiomics improve response prediction in soft-tissue sarcomas treated by neoadjuvant chemotherapy.
Amandine Crombé,Cynthia Perier,Michèle Kind,Baudouin Denis de Senneville,François Le Loarer,Antoine Italiano,Xavier Buy,Olivier Saut +7 more
TL;DR: Standard of care for patients with high‐grade soft‐tissue sarcoma (STS) are being redefined since neoadjuvant chemotherapy (NAC) has demonstrated a positive effect on patients' outcome, yet response evaluation in clinical trials still relies on RECIST criteria.
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A Multilayer Grow-or-Go Model for GBM: Effects of Invasive Cells and Anti-Angiogenesis on Growth
TL;DR: A new mathematical model is derived that takes into account the ability of proliferative cells to become invasive under hypoxic conditions; model simulations generate the multilayer structure of GBM, namely proliferation, brain invasion, and necrosis.