O
Olli Kallioniemi
Researcher at University of Helsinki
Publications - 376
Citations - 44711
Olli Kallioniemi is an academic researcher from University of Helsinki. The author has contributed to research in topics: Cancer & Prostate cancer. The author has an hindex of 90, co-authored 353 publications receiving 42021 citations. Previous affiliations of Olli Kallioniemi include European Bioinformatics Institute & Åbo Akademi University.
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An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast cancer
Aline Mamo,Luca Cavallone,Sukru Tuzmen,Catherine Chabot,Cristiano Ferrario,Saima Hassan,Henrik Edgren,Henrik Edgren,Olli Kallioniemi,Olli Kallioniemi,Olga Aleynikova,Ewa Przybytkowski,K. Malcolm,Spyro Mousses,Patricia N. Tonin,Patricia N. Tonin,Mark Basik +16 more
TL;DR: It is found that low ARID1A RNA or nuclear protein expression is associated with more aggressive breast cancer phenotypes, such as high tumor grade, in two independent cohorts of over 200 human breast cancer cases each.
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Cathepsin D expression detected by immunohistochemistry has independent prognostic value in axillary node-negative breast cancer.
TL;DR: Results indicate that CD expression determined by immunohistochemistry is a powerful prognostic factor in axillary node-negative breast cancer.
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Arachidonic Acid Pathway Members PLA2G7, HPGD, EPHX2, and CYP4F8 Identified as Putative Novel Therapeutic Targets in Prostate Cancer
Paula Vainio,Santosh Gupta,Kirsi Ketola,Tuomas Mirtti,John Patrick Mpindi,Pekka Kohonen,Vidal Fey,Merja Perälä,Frank Smit,Gerald W. Verhaegh,Jack A. Schalken,Kalle Alanen,Olli Kallioniemi,Olli Kallioniemi,Olli Kallioniemi,Kristiina Iljin,Kristiina Iljin +16 more
TL;DR: The results showed that the PLA2G7, HPGD, EPHX2, and CYP4F8 genes are highly expressed in prostate cancer and inhibition of these enzymes may be particularly powerful when combined with other treatments, such as androgen deprivation or induction of oxidative stress.
Journal Article
Deletion of chromosome 17p loci in breast cancer cells detected by fluorescence in situ hybridization.
Kouji Matsumura,Anne Kallioniemi,Olli Kallioniemi,Ling-Chun Chen,Helene S. Smith,Daniel Pinkel,Joe W. Gray,F. M. Waldman +7 more
TL;DR: The data suggest that the dominant mechanism of allelic loss at 17p in breast cancer is a physical deletion and that analysis of deletions by fluorescence in situ hybridization is a rapid and sensitive approach to studying chromosomal aberrations.
Journal Article
Genetic changes in intraductal breast cancer detected by comparative genomic hybridization.
TL;DR: It is concluded that many of the common genetic changes in IDC may take place before development of invasive growth, however, a simple linear progression model may not always account for the DCIS-IDC transition.