Olusegun J. Ariwodola

TL;DR: It is demonstrated that, at perisomatic synapses in the rat hippocampus, ethanol enhances presynaptic GABAB autoreceptor function and that this interaction reduces the overall potentiating effect of ethanol at these synapses, suggesting that an interaction between ethanol and presynptic GABABAutoreceptor activity regulates the ethanol sensitivity of GABAergic synapses.

TL;DR: This characterization of the acute actions of des-IGF-1 at hippocampal excitatory synapses may provide insight into the mechanism by which long-term increases in plasma IGF-1 impart cognitive benefits in aged rats.

TL;DR: It is discovered that early-life stress decreases the activity of a specific class of potassium channels and increases the intrinsic excitability of BLA neurons and present evidence that enhancing the function of these channels normalizes BLA excitability and attenuates anxiety-like behaviors.

TL;DR: EtOH increases excitability of pyramidal neurons indirectly by inhibiting the KA-R-dependent drive of γ-aminobutyric acid (GABA)ergic interneurons, and it is postulated that this effect may explain, in part, some of the paradoxical excitatory actions of this widely abused substance.

TL;DR: It is suggested that disruption of accumbal core NMDA receptor-dependent plasticity may represent a synaptic correlate associated with ethanol-induced locomotor sensitization and increased propensity to consume ethanol.