O
Omar S. Mabrouk
Researcher at University of Michigan
Publications - 45
Citations - 2609
Omar S. Mabrouk is an academic researcher from University of Michigan. The author has contributed to research in topics: Dopamine & Microdialysis. The author has an hindex of 25, co-authored 44 publications receiving 2172 citations. Previous affiliations of Omar S. Mabrouk include Case Western Reserve University & University of Ferrara.
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Journal ArticleDOI
Mesolimbic dopamine signals the value of work
Arif A. Hamid,Jeffrey R. Pettibone,Omar S. Mabrouk,Vaughn L. Hetrick,Robert Schmidt,Caitlin M. Vander Weele,Robert T. Kennedy,Brandon J. Aragona,Joshua D. Berke +8 more
TL;DR: The results indicate that dopamine conveys a single, rapidly evolving decision variable, the available reward for investment of effort, which is employed for both learning and motivational functions.
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In Vivo Neurochemical Monitoring using Benzoyl Chloride Derivatization and Liquid Chromatography – Mass Spectrometry
TL;DR: A high performance liquid chromatography-tandem mass spectrometry method that utilizes benzoyl chloride for determination of the most common low molecular weight neurotransmitters and metabolites is presented, revealing complex GABAergic control over mesolimbic processes.
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Evidence for the preferential involvement of 5-HT2A serotonin receptors in stress- and drug-induced dopamine release in the rat medial prefrontal cortex.
Elizabeth A. Pehek,Elizabeth A. Pehek,Christine Nocjar,Christine Nocjar,Bryan L. Roth,Tara A Byrd,Omar S. Mabrouk,Omar S. Mabrouk +7 more
TL;DR: Results indicate that stimulation of cortical 5-HT2A receptors increases the release of dopamine from the mesocortical system, and suggest that this effect may be mediated by increases in glutamate release from corticotegmental projections to the VTA.
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Benzoyl chloride derivatization with liquid chromatography???mass spectrometry for targeted metabolomics of neurochemicals in biological samples
TL;DR: A high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method that utilizes benzoyl chloride labeling for 70 neurologically relevant compounds, including catecholamines, indoleamines, amino acids, polyamines, trace amines, antioxidants, energy compounds, and their metabolites is reported.
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Enkephalin Surges in Dorsal Neostriatum as a Signal to Eat
TL;DR: In this article, enkephalin surges in an anteromedial quadrant of dorsal neostriatum contribute to generating intense consumption of palatable food. But, their results were limited to rats.