O
Ondrej Sprušanský
Researcher at Slovak Academy of Sciences
Publications - 10
Citations - 63
Ondrej Sprušanský is an academic researcher from Slovak Academy of Sciences. The author has contributed to research in topics: Streptomyces aureofaciens & Gene. The author has an hindex of 4, co-authored 10 publications receiving 60 citations. Previous affiliations of Ondrej Sprušanský include University of Georgia.
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Journal ArticleDOI
The Streptomyces aureofaciens homologue of the whiB gene is essential for sporulation; its expression correlates with the developmental stage.
Jan Kormanec,Beatrica Sevcikova,Ondrej Sprušanský,Oldřich Benada,Olga Kofroňová,Renata Novakova,Bronislava Řežuchová,Laura Potúčková,Dagmar Homerova +8 more
TL;DR: The disruption blocked differentiation at a stage between the formation of aerial mycelium and the development of mature spores, producing white aerial hyphae without septation.
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Expression of the gap gene encoding glyceraldehyde-3-phosphate dehydrogenase of Streptomyces aureofaciens requires GapR, a member of the AraC/XylS family of transcriptional activators.
TL;DR: A direct role of GapR in regulation of gap expression in S. aureofaciens is indicated, suggesting the presence of a second GAPDH which is sufficient to ensure growth.
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Identification of DNA-binding proteins involved in regulation of expression of the Streptomyces aureofaciens sigF gene, which encodes sporulation sigma factor σF
TL;DR: In this article, the location of a specific binding site of the repressor-like protein (RsfA) was determined by gel mobility-shift assays of promoter deletion fragments and by DNase I footprinting analysis.
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Functional Analysis of the Single Est1/Ebs1 Homologue in Kluyveromyces lactis Reveals Roles in both Telomere Maintenance and Rapamycin Resistance
TL;DR: Functional analysis of the sole Est1/Ebs1 homologue in the related budding yeast Kluyveromyces lactis shows that similar to other Est1s, KlEst1 is required for normal telomere maintenance in vivo and full telomerase primer extension activity in vitro and presents an attractive model system for analyzing members of this multifunctional protein family.
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Cloning of the putative aldehyde dehydrogenase, aldA, gene from Streptomyces aureofaciens.
TL;DR: All three genes formed an operon, consisting of geneorf251, with a high homology to a conserved gene present only in archæabacteria, and thealdA andadhA genes homologous to various eukaryotic and prokaryotic aldehyde- and alcohol-dehydrogenases, with maximum homologies to the phenylacetaldehyde dehydrogenases and arylalcohol dehydrogenase, respectively.