O
Oriol Sibila
Researcher at University of Barcelona
Publications - 164
Citations - 4151
Oriol Sibila is an academic researcher from University of Barcelona. The author has contributed to research in topics: Medicine & Bronchiectasis. The author has an hindex of 28, co-authored 126 publications receiving 2901 citations. Previous affiliations of Oriol Sibila include University of Texas Health Science Center at San Antonio & Carlos III Health Institute.
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Journal ArticleDOI
Effect of Corticosteroids on Treatment Failure Among Hospitalized Patients With Severe Community-Acquired Pneumonia and High Inflammatory Response A Randomized Clinical Trial
Antoni Torres,Oriol Sibila,Miquel Ferrer,Eva Polverino,Rosario Menéndez,Josep Mensa,Albert Gabarrus,Jacobo Sellares,Marcos I. Restrepo,Marcos I. Restrepo,Antonio Anzueto,Antonio Anzueto,Michael S. Niederman,Carles Agustí +13 more
TL;DR: Among patients with severe community-acquired pneumonia and high initial inflammatory response, the acute use of methylprednisolone compared with placebo decreased treatment failure, and these findings would support the use of corticosteroids as adjunctive treatment in this clinical population.
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Do chronic respiratory diseases or their treatment affect the risk of SARS-CoV-2 infection?
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The first tissue-engineered airway transplantation: 5-year follow-up results
Alessandro Gonfiotti,Massimo Osvaldo Jaus,Daniel Barale,Silvia Baiguera,Camilla E. Comin,Federico Lavorini,Giovanni A. Fontana,Oriol Sibila,Giovanni Rombolà,Philipp Jungebluth,Paolo Macchiarini +10 more
TL;DR: Clinical results provide evidence that a tissue-engineering strategy including decellularisation of a human trachea, autologous epithelial and stem-cell culture and differentiation, and cell-scaffold seeding with a bioreactor is safe and promising.
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Neutrophil Elastase Activity Is Associated with Exacerbations and Lung Function Decline in Bronchiectasis
James D. Chalmers,Kelly Moffitt,Guillermo Suarez-Cuartin,Oriol Sibila,Simon Finch,Elizabeth Furrie,Alison J. Dicker,Karolina Wrobel,J. Stuart Elborn,Brian Walker,S. Lorraine Martin,Sara E. Marshall,Jeffrey T.-J. Huang,Thomas C. Fardon +13 more
TL;DR: Elevated sputum elastase activity was associated with a higher frequency of exacerbations but was not independently associated with mortality, and candidate biomarkers were tested for their relationship with cross‐sectional markers of disease severity and future risk in adults with bronchiectasis.
Journal ArticleDOI
Neutrophil extracellular traps are associated with disease severity and microbiota diversity in patients with chronic obstructive pulmonary disease
Alison J. Dicker,Megan Crichton,Eleanor G. Pumphrey,Andrew Cassidy,Guillermo Suarez-Cuartin,Oriol Sibila,Elizabeth Furrie,Christopher J. Fong,Wasyla Ibrahim,Gill Brady,Gisli G. Einarsson,J. Stuart Elborn,J. Stuart Elborn,Stuart Schembri,Sara E. Marshall,Colin N. A. Palmer,James D. Chalmers +16 more
TL;DR: NET formation is increased in patients with severe COPD and associated with more frequent exacerbations and a loss of microbiota diversity.