Silvia Baiguera

TL;DR: These findings, together with increased levels of regenerative-associated plasma factors, strongly suggest stem-cell homing and cell-mediated wound repair, extracellular matrix remodelling, and neovascularisation of the graft are key factors for successful clinical outcome.

TL;DR: Clinical results provide evidence that a tissue-engineering strategy including decellularisation of a human trachea, autologous epithelial and stem-cell culture and differentiation, and cell-scaffold seeding with a bioreactor is safe and promising.

TL;DR: In this article, a decellularization protocol was proposed to provide fundamental biochemical cues to the seeded cells to provide tissue-specific signals that contribute to the expression of the requested cellular phenotype.

TL;DR: This paper discusses this novel approach to tissue engineering replacement using three‐dimensional biologic scaffolds composed of allogeneic extracellular scaffolds derived from nonautologous sources and recellularized with autologous stem cells or differentiated cells, and reviews information that can lead to a better understanding of stem cell recruitment and/or mobilization and site‐specific tissue protection.

TL;DR: The results demonstrated that genipin cross-linked electrospun gelatin mats loaded with VEGF could be part of a useful strategy to stimulate and induce angiogenesis in tissue engineered applications.