O
Oscar Rovira
Researcher at Carlos III Health Institute
Publications - 5
Citations - 488
Oscar Rovira is an academic researcher from Carlos III Health Institute. The author has contributed to research in topics: Insulin & Circulating MicroRNA. The author has an hindex of 4, co-authored 5 publications receiving 372 citations.
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Journal ArticleDOI
Profiling of Circulating MicroRNAs Reveals Common MicroRNAs Linked to Type 2 Diabetes That Change With Insulin Sensitization
Francisco J. Ortega,Josep M. Mercader,José María Moreno-Navarrete,Oscar Rovira,Ester Guerra,Eduardo Esteve,Gemma Xifra,Cristina Martínez,Wifredo Ricart,Jennifer Rieusset,Sophie Rome,Monika Karczewska-Kupczewska,Monika Karczewska-Kupczewska,Marek Straczkowski,Marek Straczkowski,José Manuel Fernández-Real +15 more
TL;DR: This study depicts the close association between variations in circulating miRNAs and T2D and their potential relevance in insulin sensitivity.
Journal ArticleDOI
Decreased lipid metabolism but increased FA biosynthesis are coupled with changes in liver microRNAs in obese subjects with NAFLD.
Jèssica Latorre,J M Moreno-Navarrete,Josep M. Mercader,Mònica Sabater,Oscar Rovira,Jordi Girones,Wilfredo Ricart,José Manuel Fernández-Real,F Ortega +8 more
TL;DR: This study confirms decreased liver glucose and lipid metabolism but increased FA biosynthesis coupled with changes in five unique miRNAs in obese patients with NAFLD.
Journal ArticleDOI
Surgery-Induced Weight Loss Is Associated With the Downregulation of Genes Targeted by MicroRNAs in Adipose Tissue.
Francisco J. Ortega,Josep M. Mercader,José María Moreno-Navarrete,Lara Nonell,Eulàlia Puigdecanet,José I. Rodriquez-Hermosa,Oscar Rovira,Gemma Xifra,Ester Guerra,María Moreno,Dolores Mayas,Natalia Moreno-Castellanos,Natalia Moreno-Castellanos,Jose A Fernández-Formoso,Wifredo Ricart,Francisco J. Tinahones,David Torrents,María M. Malagón,María M. Malagón,José Manuel Fernández-Real +19 more
TL;DR: Current findings suggest impaired miRNA target gene expression in obese AT in close association with inflammation, both improving after weight loss.
Journal ArticleDOI
Circulating Irisin and Myostatin as Markers of Muscle Strength and Physical Condition in Elderly Subjects.
Cristina Planella-Farrugia,Ferran Comas,Mònica Sabater-Masdeu,María Moreno,José María Moreno-Navarrete,José María Moreno-Navarrete,Oscar Rovira,Wifredo Ricart,Wifredo Ricart,José Manuel Fernández-Real,José Manuel Fernández-Real +10 more
TL;DR: Circulating irisin, but not myostatin, constitutes a marker for improved muscular performance in elderly subjects and was significantly decreased in those participants with strength loss at the end of the study.
Circulating MicroRNAs Reveals Common MicroRNAs Linked to Type 2 DiabetesThatChange
Oscar Rovira,Ester Guerra,Eduardo Esteve,Gemma Xifra,Wifredo Ricart,Jennifer Rieusset,Sophie Rome,Monika Karczewska-Kupczewska,Marek Straczkowski +8 more
TL;DR: The results of this study give promising evidence for future analyses using circulating miRNAs to examine the pathophysiology of T2D, and the modification sobserved after metabolic changesinduced by metformin, insulin, andinsulin plus intralipid infusions demonstrates that components of this pro-leverage are regulated in parallel toinsulin action.