O
Oscar Valiente
Researcher at Center of Molecular Immunology
Publications - 11
Citations - 545
Oscar Valiente is an academic researcher from Center of Molecular Immunology. The author has contributed to research in topics: Ganglioside & Gracilaria. The author has an hindex of 8, co-authored 10 publications receiving 528 citations.
Papers
More filters
Journal Article
Gangliosides Expressed in Human Breast Cancer
Gilda Marquina,Hatsue Waki,Luis E. Fernández,Kazuo Kon,Adriana Carr,Oscar Valiente,Rolando Pérez,Susumu Ando +7 more
TL;DR: The finding that unusual gangliosides are expressed in breast tumors may provide the basis for their immunological diagnosis and vaccine therapy.
Journal ArticleDOI
Enhancement of the immune response to poorly immunogenic gangliosides after incorporation into very small size proteoliposomes (VSSP).
Francisco Estevez,Adriana Carr,Leobaldo Solorzano,Oscar Valiente,Circe Mesa,Osquel Barroso,Gustavo Sierra,Luis E. Fernández +7 more
TL;DR: The immunological and physicochemical properties of very small size proteoliposomes (VSSP) obtained by using anionic detergents to incorporate gangliosides into the outer membrane protein complex (OMPC) of N. meningitidis are reported.
Journal ArticleDOI
Isolation and characterization of an antitumor active agar-type polysaccharide of Gracilaria dominguensis.
Luis E. Fernández,Oscar Valiente,Virgilio Mainardi,José Luis Bello,Hermán Vélez,Arístides Rosado +5 more
TL;DR: Cold water extraction of the red alga Gracilaria dominguensis, followed by cetyltrimethylammonium bromide fractionation, gave a highly sulfated, agar-type polysaccharide which inhibited the transplantation of Ehrlich ascites carcinoma in mice.
Journal ArticleDOI
A purified GM3 ganglioside conjugated vaccine induces specific, adjuvant-dependent and non-transient antitumour activity against B16 mouse melanoma in vitro and in vivo.
Adriana Carr,Zaima Mazorra,D F Alonso,Circe Mesa,Oscar Valiente,Daniel E. Gomez,Rolando Pérez,Luis E. Fernández +7 more
TL;DR: The present data indicate the molecular specificity of GM3/VSSP vaccine as well as the adjuvant-dependent and non-transient character of tumour protection in the B16 mouse model and suggest that an appropriate GM3 vaccine may be capable of inducing prolonged tumours protection in melanoma patients.
Journal ArticleDOI
Agar Polysaccharides from the Red Seaweeds Gracilaria domingensis Sonder ex Kützing and Gracilaria mammillaris (Montagne) Howe
TL;DR: The main structural features of the gel-forming polysaccharides of the red seaweeds, Gracilaria domingensis and Gracilia mammillaris based on 1 H and 13 C N are reported and evidence for the presence of the biological precursor of agarobiose repeat units is presented.