O
Otmar Schober
Researcher at University of Münster
Publications - 259
Citations - 9939
Otmar Schober is an academic researcher from University of Münster. The author has contributed to research in topics: Positron emission tomography & In vivo. The author has an hindex of 52, co-authored 259 publications receiving 9413 citations. Previous affiliations of Otmar Schober include European Institute.
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Journal ArticleDOI
Reduced-intensity chemotherapy and PET-guided radiotherapy in patients with advanced stage Hodgkin's lymphoma (HD15 trial): a randomised, open-label, phase 3 non-inferiority trial
Andreas Engert,Heinz Haverkamp,Carsten Kobe,Jana Markova,Christoph Renner,A. D. Ho,Josée M. Zijlstra,Zdenek Kral,Michael Fuchs,Michael Hallek,Lothar Kanz,Hartmut Döhner,Bernd Dörken,Nicole Engel,Max S. Topp,Susanne Klutmann,Holger Amthauer,Andreas Bockisch,Regine Kluge,Clemens Kratochwil,Otmar Schober,Richard Greil,Reinhard Andreesen,Michael Kneba,Michael Pfreundschuh,Harald Stein,Hans Theodor Eich,Rolf-Peter Müller,Markus Dietlein,Peter Borchmann,Volker Diehl +30 more
TL;DR: Treatment with six cycles of BEACOPP(escalated) followed by PET-guided radiotherapy was more effective in terms of freedom from treatment failure and less toxic than eight cycles of the same chemotherapy regimen, and should be the treatment of choice for advanced stage Hodgkin's lymphoma.
Journal ArticleDOI
Whole-body MR imaging for detection of bone metastases in children and young adults: comparison with skeletal scintigraphy and FDG PET.
Heike E. Daldrup-Link,Christiane Franzius,Thomas M. Link,Daniela Laukamp,Joachim Sciuk,Heribert Jürgens,Otmar Schober,Ernst J. Rummeny +7 more
TL;DR: Whole-body MR imaging has a higher sensitivity than skeletal scintigraphy for the detection of bone marrow metastases but a lower sensitivity than FDG PET.
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High-Density Lipoproteins and Their Constituent, Sphingosine-1-Phosphate, Directly Protect the Heart Against Ischemia/Reperfusion Injury In Vivo via the S1P3 Lysophospholipid Receptor
Gregor Theilmeier,Christoph Schmidt,Jörg Herrmann,Petra Keul,Michael Schäfers,Ilka Herrgott,Jan Mersmann,Jan Larmann,Sven Hermann,Jörg Stypmann,Otmar Schober,Reinhard Hildebrand,Rainer Schulz,Gerd Heusch,Michael Haude,Karin von Wnuck Lipinski,Christine Herzog,Martina Schmitz,Raimund Erbel,Jerold Chun,Bodo Levkau +20 more
TL;DR: The data demonstrate that HDL and its constituent, S1P, acutely protect the heart against ischemia/reperfusion injury in vivo via an S 1P3-mediated and NO-dependent pathway and a rapid therapeutic elevation of S1p-containing HDL plasma levels may be beneficial in patients at high risk of acute myocardial ischemIA.
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Fluorine-18 fluorodeoxyglucose positron emission tomography in thyroid cancer: results of a multicentre study.
Frank Grünwald,Thomas Kälicke,U. Feine,R. Lietzenmayer,Klemens Scheidhauer,Markus Dietlein,Otmar Schober,Hartmut Lerch,Katja Brandt-Mainz,Wolfgang Burchert,Gerhard Hiltermann,U. Cremerius,Hans-Jürgen Biersack +12 more
TL;DR: FDG-PET is a sensitive method in the follow-up of thyroid cancer which should be considered in all patients suffering from differentiated thyroid cancer with suspected recurrence and/or metastases, and particularly in those with elevated thyroglobulin values and negative WBS.
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FDG-PET for detection of osseous metastases from malignant primary bone tumours: comparison with bone scintigraphy
TL;DR: The sensitivity, specificity and accuracy of FDG-PET in the detection of osseous metastases from Ewing's sarcomas are superior to those of bone scintigraphy, however, in the Detection of osSEous metastase from osteosarcoma,FDG- PET seems to be less sensitive than bone scintsigraphy.