O
Owen J. Marshall
Researcher at Menzies Research Institute
Publications - 37
Citations - 2389
Owen J. Marshall is an academic researcher from Menzies Research Institute. The author has contributed to research in topics: Chromatin & Transcription factor. The author has an hindex of 15, co-authored 28 publications receiving 2040 citations. Previous affiliations of Owen J. Marshall include University of Cambridge & Royal Children's Hospital.
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PerlPrimer: cross-platform, graphical primer design for standard, bisulphite and real-time PCR
TL;DR: UNLABELLED PerlPrimer is a cross-platform graphical user interface application for the design of primers for standard, bisulphite and real-time PCR, and sequencing that incorporates highly accurate melting-temperature and primer-dimer prediction algorithms.
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Neocentromeres: New Insights into Centromere Structure, Disease Development, and Karyotype Evolution
TL;DR: Recent research has focused on the role of neocentromeres in evolution and speciation, as well as in disease development and the understanding of the organization and epigenetic maintenance of the centromere.
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Active transcription and essential role of RNA polymerase II at the centromere during mitosis
F. Lyn Chan,Owen J. Marshall,Richard Saffery,Bowon Kim,Elizabeth D. Earle,K. H. Andy Choo,Lee H. Wong +6 more
TL;DR: An essential role of RNAPII is demonstrated in the transcription of α-satellite DNA, binding of centromere protein C, and the proper functioning of the mitotic kinetochore.
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Cell-Type-Specific Profiling of Gene Expression and Chromatin Binding without Cell Isolation: Assaying RNA Pol II Occupancy in Neural Stem Cells
Tony D. Southall,Katrina S. Gold,Boris Egger,Catherine M. Davidson,Elizabeth E. Caygill,Owen J. Marshall,Andrea H. Brand +6 more
TL;DR: It is shown that TaDa can be used to identify transcribed genes in a cell-type-specific manner with considerable temporal precision, enabling the identification of differential gene expression between neuroblasts and the neuroepithelial cells from which they derive.
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Contrasting roles of condensin I and condensin II in mitotic chromosome formation
Lydia C. Green,Paul Kalitsis,Tsz M. Chang,Miri Cipetic,Ji Hun Kim,Owen J. Marshall,Lynne Turnbull,Cynthia B. Whitchurch,Paola Vagnarelli,Kumiko Samejima,William C. Earnshaw,K. H. Andy Choo,Damien F. Hudson +12 more
TL;DR: It is concluded thatcondensin II is required primarily to provide rigidity by establishing an initial chromosome axis around which condensin I can arrange loops of chromatin.