P
P. Collins
Researcher at Leeds General Infirmary
Publications - 10
Citations - 327
P. Collins is an academic researcher from Leeds General Infirmary. The author has contributed to research in topics: Protoporphyrin IX & Photodynamic therapy. The author has an hindex of 4, co-authored 10 publications receiving 321 citations.
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Journal ArticleDOI
Adverse reactions following pulsed tunable dye laser treatment of port wine stains in 701 patients.
TL;DR: The observations show that there is a small but definite risk of atrophic scarring with a predisposition for younger patients and the need for a full discussion of scarring risk in patients with PWS undergoing treatment with the PTDL.
Journal ArticleDOI
Improved response of plaque psoriasis after multiple treatments with topical 5-aminolaevulinic acid photodynamic therapy.
Dominic J. Robinson,P. Collins,Mark R. Stringer,David I. Vernon,G.I. Stables,Stanley B. Brown,R.A. Sheehan‐Dare +6 more
TL;DR: Although clinical efficacy improved with multiple treatments with photodynamic therapy, unpredictable response and patient discomfort make ALA-PDT unsuitable for the treatment of psoriasis.
Journal ArticleDOI
The variable response of plaque psoriasis after a single treatment with topical 5‐aminolaevulinic acid photodynamic therapy
TL;DR: It is demonstrated that only in those patients who showed clearance of psoriasis was there a relationship between photodynamic dose and clinical response, and effectiveness may improve by achieving consistent proto porphyrin IX levels or by using multiple treatments.
Journal ArticleDOI
The Accumulation of Protoporphyrin IX in Plaque Psoriasis After Topical Application of 5-Aminolevulinic Acid Indicates a Potential for Superficial Photodynamic Therapy
TL;DR: It is shown that the characteristic fluorescence emission of protoporphyrin IX increases in intensity within the 6-h period following application of 5-ami-nolevulinic acid, suggesting that there is a potential for superficial photodynamic therapy.
Proceedings ArticleDOI
Establishment of treatment parameters for ALA-PDT of plaque psoriasis
TL;DR: A correlation of fluorescence measurements with clinical response of plaques indicates that the effectiveness of PDT is dominated by the level of PpIX at the onset of treatment, and is much less dependent upon light dose.