P
P. Goldmann
Researcher at Ruhr University Bochum
Publications - 1
Citations - 294
P. Goldmann is an academic researcher from Ruhr University Bochum. The author has contributed to research in topics: Troponin I & Myocyte. The author has an hindex of 1, co-authored 1 publications receiving 276 citations.
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Increased Ca2+-sensitivity of the contractile apparatus in end-stage human heart failure results from altered phosphorylation of contractile proteins
J. van der Velden,Zoltán Papp,R. Zaremba,Nicky M. Boontje,J. W. de Jong,V. J. Owen,P. B.J. Burton,P. Goldmann,Kornelia Jaquet,Ger J.M. Stienen +9 more
TL;DR: The increased Ca(2+)-responsiveness of the contractile apparatus in end-stage failing human hearts cannot be explained by a shift in contractile protein isoforms, but results from the complex interplay between changes in the phosphorylation status of MLC-2 and TnI.