P
P. P. M. Kooij
Researcher at Erasmus University Rotterdam
Publications - 43
Citations - 9792
P. P. M. Kooij is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Octreotide & Radionuclide therapy. The author has an hindex of 36, co-authored 43 publications receiving 9238 citations.
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Journal ArticleDOI
Somatostatin receptor scintigraphy with [111In-DTPA-d-Phe1]- and [123I-Tyr3]-octreotide: the Rotterdam experience with more than 1000 patients
E. P. Krenning,Dirk Jan Kwekkeboom,Willem H. Bakker,W. A. P. Breeman,P. P. M. Kooij,H. Y. Oei,M. van Hagen,P. T. E. Postema,M. De Jong,Jean Claude Reubi,Theo J. Visser,Ambroos E.M. Reijs,Leo J Hofland,Jan W. Koper,S. W. J. Lamberts +14 more
TL;DR: The successful application of radiolabelled octreotide in scintigraphy indicates the possible usefulness of other radiolABelled peptides, either native peptides or derivatives of these, in, for example, nuclear oncology.
Journal ArticleDOI
Treatment With the Radiolabeled Somatostatin Analog [177Lu-DOTA0,Tyr3]Octreotate: Toxicity, Efficacy, and Survival
Dik J. Kwekkeboom,Wouter W. de Herder,Boen L. Kam,Casper H.J. van Eijck,Martijn van Essen,P. P. M. Kooij,Richard A Feelders,Maarten O. van Aken,Eric P. Krenning +8 more
TL;DR: Treatment with peptide receptor radionuclide therapy with the radiolabeled somatostatin analog [(177)Lu-DOTA(0),Tyr(3)]octreotate has few adverse effects and compares favorably to the limited number of alternative treatment modalities.
Journal ArticleDOI
Radiolabeled Somatostatin Analog [177Lu-DOTA0,Tyr3]Octreotate in Patients With Endocrine Gastroenteropancreatic Tumors
Dik J. Kwekkeboom,Jaap J.M. Teunissen,Willem H. Bakker,P. P. M. Kooij,Wouter W. de Herder,Richard A Feelders,Casper H.J. van Eijck,Jan-Paul Esser,Boen L. Kam,Eric P. Krenning +9 more
TL;DR: Treatment with 177Lu-octreotate results in tumor remission in a high percentage of patients with GEP tumors, and results are better in patients with a limited tumor load.
Journal ArticleDOI
Localisation of endocrine-related tumours with radioiodinated analogue of somatostatin
Eric P. Krenning,Wouter A.P. Breeman,P. P. M. Kooij,Johan S. Laméris,Willem H. Bakker,Jan W. Koper,L. Ausema,Jean Claude Reubi,S. W. J. Lamberts +8 more
TL;DR: Radioiodinated tyr-3-octreotide can label somatostatin receptors in endocrine-related tumours in vivo and can therefore be used for tumour localisation.
Journal Article
Somatostatin Receptor Scintigraphy with Indium-111-DTPA-D-Phe-1-Octreotide in Man: Metabolism, Dosimetry and Comparison with Iodine-123-Tyr-3-Octreotide
E.P. Krenning,Willem H. Bakker,P. P. M. Kooij,W. A. P. Breeman,H. Y. Oei,de Jong M,Jean Claude Reubi,Theo J. Visser,C. Bruns,Dirk Jan Kwekkeboom +9 more
TL;DR: 111In-DTPA-D-Phe-1-octreotide appears to be a sensitive somatostatin receptor-positive tissue-seeking radiopharmaceutical with some remarkable advantages: easy preparation, general availability, appropriate half-life and absence of major interference in the upper abdominal region, because of its renal clearance.