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P.S. Chandra

Researcher at All India Institute of Medical Sciences

Publications -  29
Citations -  509

P.S. Chandra is an academic researcher from All India Institute of Medical Sciences. The author has contributed to research in topics: Aneurysm & Epilepsy. The author has an hindex of 11, co-authored 29 publications receiving 431 citations.

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Awake craniotomy versus surgery under general anesthesia for resection of intrinsic lesions of eloquent cortex—A prospective randomised study

TL;DR: A prospective randomized comparative study of results of surgery under awake versus surgery under general anesthesia for intrinsic eloquent area lesions for intrinsic brain tumors in eloquent areas finds that awake surgery may achieve more aggressive tumor resection and minimize postoperative neurological morbidity.
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FAT1 acts as an upstream regulator of oncogenic and inflammatory pathways, via PDCD4, in glioma cells

TL;DR: This study identifies a novel signaling mechanism mediated by FAT1 in regulating the activity of PDCD4 and thereby the key transcription factor AP-1, which then affects known mediators of neoplasia and inflammation.
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Surgical considerations for 'intrinsic' brainstem gliomas: proposal of a modification in classification.

TL;DR: The surgical management of intrinsic brain stem tumors presents a surgical challenge; radical excision yielded a good outcome in the majority of cases and the authors propose a classification system for 'intrinsic' brainstem tumors for defining surgical strategy.
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Role of concordance between ictal-subtracted SPECT and PET in predicting long-term outcomes after epilepsy surgery.

TL;DR: In both temporal and extratemporal epilepsies the concordance of the iSPECT/FDG-PET with the MRI/vEEG correlated with a better 5-year outcome, but this correlation was not found for the temporal epilepsy, where the MRI and vEEG were the most important prognostic parameters.