P
Pablo J. Schwarzbaum
Researcher at University of Buenos Aires
Publications - 65
Citations - 1088
Pablo J. Schwarzbaum is an academic researcher from University of Buenos Aires. The author has contributed to research in topics: Extracellular & Purinergic receptor. The author has an hindex of 20, co-authored 60 publications receiving 997 citations. Previous affiliations of Pablo J. Schwarzbaum include National Scientific and Technical Research Council & University of Innsbruck.
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Journal ArticleDOI
Homeostasis of Extracellular ATP in Human Erythrocytes
Nicolas Montalbetti,María Florencia Leal Denis,Omar Pedro Pignataro,Omar Pedro Pignataro,Eiry Kobatake,Eduardo R. Lazarowski,Pablo J. Schwarzbaum +6 more
TL;DR: Using the luciferin-luciferase reaction in off-line luminometry, both direct adenylyl cyclase activation by forskolin and indirect activation through β-adrenergic stimulation with isoproterenol-enhanced [ATP]e in a concentration-dependent manner are found.
Journal ArticleDOI
Membrane-metabolic coupling and ion homeostasis in anoxia-tolerant and anoxia-intolerant hepatocytes
TL;DR: In trout hepatocytes, under normoxia and under chemical anoxia, inhibition of ATP consumption by the Na+ pump induced a decrease in ATP production of the same magnitude, which led to a rapid depletion of cells, similar to that observed in the anoxic rat hepatocyte.
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Contrasting effects of temperature acclimation on mechanisms of ionic regulation in a eurythermic and a stenothermic species of freshwater fish (Rutilus rutilus and salvelinus alpinus)
TL;DR: In the kidney tissue of cold acclimated R. rutilus, the maximal number of binding sites per mg protein (Bmax) and the activity of Na+, K+-ATPase, as well as tissue respiration increased significantly, whereas in S. alpinus no changes in these variables were observed.
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Coupling of Energy Supply and Energy Demand in Isolated Goldfish Hepatocytes
TL;DR: The allocation of metabolic energy under fluctuating conditions of supply and demand was studied in isolated goldfish hepatocytes and an apparent mismatch between supply andDemand ofATP is interpreted as reflecting the flexibility of energy allocation under energy-limiting conditions.
Journal ArticleDOI
Oxygen-dependent energetics of anoxia-tolerant and anoxia-intolerant hepatocytes.
TL;DR: Protein synthesis was suppressed in both cell types under hypoxia, whereas Na(+)/K(+)-ATPase activity decreased in trout but not in goldfish hepatocytes, emphasising the importance of membrane function in these cells during conditions of limited energy supply.