P
Pål Nyrén
Researcher at Stockholm University
Publications - 29
Citations - 3188
Pål Nyrén is an academic researcher from Stockholm University. The author has contributed to research in topics: Rhodospirillum rubrum & Inorganic pyrophosphatase. The author has an hindex of 13, co-authored 29 publications receiving 3134 citations. Previous affiliations of Pål Nyrén include Royal Institute of Technology.
Papers
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Journal ArticleDOI
Real-Time DNA Sequencing Using Detection of Pyrophosphate Release
TL;DR: An approach for real-time DNA sequencing without the need for electrophoresis has been developed that relies on the detection of DNA polymerase activity by an enzymatic luminometric inorganic pyrophosphate (PPi) detection assay (ELIDA) and the possibility for parallel processing of many samples in an automated manner is discussed.
Patent
Method of sequencing dna
TL;DR: In this paper, a method of identifying a base at a target position in a sample nucleic acid sequence is proposed. But the method is not suitable for the case of the presence of a nucleotide in the sequence.
Journal ArticleDOI
Enzymatic Method for Continuous Monitoring of Inorganic Pyrophosphate Synthesis
Pål Nyrén,Arne Lundin +1 more
TL;DR: A sensitive method for the analysis of inorganic pyrophosphate (PPi) which utilizes the enzymes ATP sulfurylase and firefly luciferase is described, which has been used for continuous monitoring of formation of PPi in Rhodospirillum rubrum chromatophores.
Journal ArticleDOI
Enzymatic method for continuous monitoring of DNA polymerase activity
TL;DR: A simple and rapid method has been developed for continuous monitoring of DNA synthesis in vitro, and the effect of an inhibitor, adriamycin, on the polymerase activity was studied.
Journal ArticleDOI
Typing of human papillomavirus by pyrosequencing.
TL;DR: Pyrosequencing was found to be a fast and efficient tool for identifying individual HPV types and has the capability of determining novel HPV types as well as HPV sequence variants harboring mutation(s).