Pallab Kar

TL;DR: Supporting evidence is provided that CBL extract possesses potent hepatoprotective capacity by ameliorating haloalkane induced liver injury in the murine model and the compound α-amyrin present in the leaf extract of C. bonplandianus has better potentiality to protect hepatocellular damages than the standard drug Silymarin.

TL;DR: The present results promise to provide new avenues to further evaluate the potential of the phytocompound taraxerol in vitro and in vivo towards its successful deployment as a SARS-CoV-2 inhibitor and combat the catastrophic COVID-19.

TL;DR: Estimation of physicochemical properties and potential toxicity of the metabolites followed by robust molecular dynamics simulations and analysis of MM-PBSA energy scoring function established deoxycylindrospermopsin as the most promising inhibitory candidate against both SARS-CoV-2 proteases.

TL;DR: Taking into account all the experimental data, it can be said that the fruits of H. salicifolia and both M. nagi and M. esculenta have good antioxidant activity compared to fruits of E. pyriformis.

TL;DR: The inhibitory potential of the phytochemicals from ethnomedicinally relevant Indian plants, including Justicia adhatoda, Ocimum sanctum and Swertia chirata, with reported antiviral activities against crucial SARS-CoV-2 proteins are estimated to be promising druggable targets for COVID-19 therapeutic research.