P
Pan Liu
Researcher at Sun Yat-sen University
Publications - 12
Citations - 208
Pan Liu is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Metastasis & Cancer research. The author has an hindex of 4, co-authored 6 publications receiving 41 citations.
Papers
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Journal ArticleDOI
FABP5 promotes lymph node metastasis in cervical cancer by reprogramming fatty acid metabolism.
Chunyu Zhang,Yuandong Liao,Pan Liu,Qiqiao Du,Yanchun Liang,Shiyin Ooi,Shuhang Qin,Shanyang He,Shuzhong Yao,Wei Wang +9 more
TL;DR: FABP5 was markedly upregulated in CCa with LNM and correlated with poor prognosis and can be regulated by miR-144-3p in hypoxia, highlighting a FA metabolism-dependent mechanism of FABp5-induced LNM.
Journal ArticleDOI
Tumor cell-derived exosomes deliver TIE2 protein to macrophages to promote angiogenesis in cervical cancer
Shi Du,Jiaxian Qian,Shuran Tan,Wenhan Li,Pan Liu,Jing Zhao,Ya Zeng,Linjuan Xu,Zehua Wang,Jianfeng Cai +9 more
TL;DR: In this paper , exosomes derived from TIE2-high cervical cancer cells were transferred to macrophages, thereby inducing TEMs and associated with the progression of cervical cancer.
Journal ArticleDOI
High expression of PTPRM predicts poor prognosis and promotes tumor growth and lymph node metastasis in cervical cancer.
Pan Liu,Chunyu Zhang,Yuandong Liao,Junxiu Liu,Jiaming Huang,Meng Xia,Ming Chen,Hao Tan,Weipeng He,Manman Xu,Tianyu Liu,Shiyin Ooi,Qiqiao Du,Shuhang Qin,Yuan Zhu,Qiaojian Zou,Wei Wang,Shuzhong Yao +17 more
TL;DR: It is demonstrated that protein tyrosine phosphatase receptor type M (PTPRM), identified from TCGA dataset, was markedly upregulated in CCa with LNM and correlated with L NM, and knockdown of PTPRM dramatically reduced LNM in vivo, suggesting that PTPRm plays an important role in the LNM of CCa.
Journal ArticleDOI
Circular RNA hsa_circ_0043280 inhibits cervical cancer tumor growth and metastasis via miR-203a-3p/PAQR3 axis.
Chunyu Zhang,Pan Liu,Jiaming Huang,Yuandong Liao,Chaoyun Pan,Junxiu Liu,Qiqiao Du,Tianyu Liu,Chunliang Shang,Shiyin Ooi,Run Chen,Meng Xia,Hongye Jiang,Manman Xu,Qiaojian Zou,Yijia Zhou,Hua Huang,Yuwen Pan,Li Yuan,Wei Wang,Shuzhong Yao +20 more
TL;DR: In this paper, a circRNA derived from the TADA2A gene (hsa_circ_0043280) was significantly downregulated in cervical cancer and that this reduction in expression was correlated with a poor prognosis.
Journal ArticleDOI
High Expression of Integrin α3 Predicts Poor Prognosis and Promotes Tumor Metastasis and Angiogenesis by Activating the c-Src/Extracellular Signal-Regulated Protein Kinase/Focal Adhesion Kinase Signaling Pathway in Cervical Cancer.
Qiqiao Du,Wei Wang,Tianyu Liu,Chunliang Shang,Jiaming Huang,Yuandong Liao,Shuhang Qin,Yili Chen,Pan Liu,Junxiu Liu,Shuzhong Yao +10 more
TL;DR: The findings may shed light on the mechanism involved in cervical cancer metastasis and highlight integrin α3 as a candidate prognostic biomarker and therapeutic target in patients with cervical cancer.