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Paola Mura
Researcher at University of Florence
Publications - 207
Citations - 8767
Paola Mura is an academic researcher from University of Florence. The author has contributed to research in topics: Dissolution testing & Dosage form. The author has an hindex of 55, co-authored 203 publications receiving 7915 citations. Previous affiliations of Paola Mura include University of Sassari & University of Santiago de Compostela.
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Analytical techniques for characterization of cyclodextrin complexes in aqueous solution: a review.
TL;DR: The purpose of the present review is to give a general overview of the main analytical tools which can be employed for the characterization of drug-cyclodextrin inclusion complexes in solution, with emphasis on their respective potential merits, disadvantages and limits.
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Analytical techniques for characterization of cyclodextrin complexes in the solid state: A review.
TL;DR: A general prospect of the principal analytical techniques which can be employed for a suitable characterization of drug-cyclodextrin systems in the solid state, evidencing their respective potential advantages and limits is presented.
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Preparation and characterisation of liposomes encapsulating ketoprofen-cyclodextrin complexes for transdermal drug delivery
TL;DR: Permeability studies of drug and drug-Cyd complexes, as such or incorporated in liposomes, performed both across artificial membranes and rat skin, highlighted a favourable effect of Cyd on drug permeation rate, due to its solubilizing action; by contrast, unexpectedly, no skin-permeation enhancer property of liposome has been evidenced.
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Interactions of ketoprofen and ibuprofen with β-cyclodextrins in solution and in the solid state
TL;DR: In this article, drug-carrier interactions were studied in aqueous solution by means of phase-solubility analysis and 13 C NMR spectroscopy, and in the solid state using differential scanning calorimetry (DSC), X-ray powder diffractometry and infrared spectrum analysis.
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Development, characterization and in vivo evaluation of benzocaine-loaded liposomes.
Paola Mura,Francesca Maestrelli,M.L. González-Rodríguez,Ilaria Michelacci,Carla Ghelardini,Antonio M. Rabasco +5 more
TL;DR: The results suggest that a suitably developed liposomal formulation of benzocaine can be of actual value for improving its clinical effectiveness in topical anaesthesia.