P
Paolo Bolognesi
Researcher at University of Ferrara
Publications - 2
Citations - 55
Paolo Bolognesi is an academic researcher from University of Ferrara. The author has contributed to research in topics: Glutamate receptor & Dopaminergic. The author has an hindex of 2, co-authored 2 publications receiving 37 citations.
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Journal ArticleDOI
Olanzapine, but not clozapine, increases glutamate release in the prefrontal cortex of freely moving mice by inhibiting D-aspartate oxidase activity
Silvia Sacchi,Vito de Novellis,Giovanna Paolone,Tommaso Nuzzo,Monica Iannotta,Carmela Belardo,Marta Squillace,Paolo Bolognesi,Elena Rosini,Zoraide Motta,Martina Frassineti,Alessandro Bertolino,Loredano Pollegioni,Michele Morari,Sabatino Maione,Francesco Errico,Alessandro Usiello +16 more
TL;DR: Results suggest that the second-generation antipsychotic olanzapine, through the inhibition of DDO activity, increases L-glutamate release in the PFC of treated mice.
Journal ArticleDOI
Leucine-rich repeat kinase 2 (LRRK2) inhibitors differentially modulate glutamate release and Serine935 LRRK2 phosphorylation in striatal and cerebrocortical synaptosomes.
Daniela Mercatelli,Paolo Bolognesi,Martina Frassineti,Clarissa Anna Pisanò,Francesco Longo,Derya R. Shimshek,Michele Morari +6 more
TL;DR: The G2019S mutation unravels a dopamine‐promoting action of LRRK2 inhibitors while blunting their effects on glutamate release, which highlights their positive potential for the treatment of PD, especially of L RRK2 mutation carriers.