E
Elena Rosini
Researcher at University of Insubria
Publications - 73
Citations - 1851
Elena Rosini is an academic researcher from University of Insubria. The author has contributed to research in topics: Amino acid & D-amino acid oxidase. The author has an hindex of 20, co-authored 62 publications receiving 1420 citations.
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Journal ArticleDOI
Lignin-degrading enzymes.
TL;DR: Recently investigations have expanded the range of natural biocatalysts involved in lignin degradation/modification and significant progress related to enzyme engineering and recombinant expression has been made, suggesting the potential (industrial) application of ligninolytic enzymes.
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Properties and applications of microbial D-amino acid oxidases: current state and perspectives.
Loredano Pollegioni,Gianluca Molla,Silvia Sacchi,Elena Rosini,Roberto Verga,Mirella S. Pilone +5 more
TL;DR: The aim of this paper is to provide an overview of the main biotechnological applications of DAAO (ranging from biocatalysis to convert cephalosporin C into 7-amino cep Halosporanic acid to gene therapy for tumor treatment) and to illustrate the advantages of using the microbial DAAOs, employing both the native and the improved DAAo variants obtained by enzyme engineering.
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D-amino acid oxidase inhibitors as a novel class of drugs for schizophrenia therapy
TL;DR: Current evidence indicates that increasing NMDA receptor function, perhaps by inhibiting DAAO-induced degradation of D-serine may alleviate symptoms in schizophrenic patients, and it has been suggested that co-administration of D -serine with a human D AAO inhibitor may be a more effective means of increasing D- Serine levels in the brain.
Journal ArticleDOI
Evolution of an acylase active on cephalosporin C
Loredano Pollegioni,S. Lorenzi,Elena Rosini,Giorgia Letizia Marcone,Gianluca Molla,Roberto Verga,Walter Cabri,Mirella S. Pilone +7 more
TL;DR: The evolved acylase variants produced are enzymes with a new substrate specificity, not found in nature, and represent a hallmark for industrial production of 7‐amino cephalosporanic acid.
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D-amino acids in foods.
TL;DR: D-AAs are present in a variety of foodstuffs, where they fulfill a relevant role in producing differences in taste and flavor and in their antimicrobial and antiaging properties from the corresponding L-enantiomers.