P
Parismita Kalita
Researcher at Indian Institute of Science
Publications - 30
Citations - 710
Parismita Kalita is an academic researcher from Indian Institute of Science. The author has contributed to research in topics: Medicine & Fasciola gigantica. The author has an hindex of 10, co-authored 24 publications receiving 408 citations. Previous affiliations of Parismita Kalita include North Eastern Hill University.
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Design of a peptide-based subunit vaccine against novel coronavirus SARS-CoV-2.
TL;DR: A new, designed multi-peptide subunit-based epitope vaccine against COVID-19, made up of 33 highly antigenic epitopes from three proteins that have a prominent role in host-receptor recognition, viral entry, and pathogenicity is presented.
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Aminoacyl-tRNA synthetases: Structure, function, and drug discovery
TL;DR: This review reviews the classification, function, and the conserved as well the appended structural architecture of these enzymes in detail, including its association with multi-synthetase complexes and their role in human diseases in terms of mutations and autoantibodies against AARSs.
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Development of multi-epitope driven subunit vaccine against Fasciola gigantica using immunoinformatics approach.
TL;DR: A multi-epitope based subunit vaccine using seven important F. gigantica proteins showed potential immunogenic efficacy by elaborating the IFN-γ and humoral response and in silico cloning was performed to create the plasmid construct of vaccine for expression in an appropriate biological system.
Posted ContentDOI
Design of a Peptide-Based Subunit Vaccine against Novel Coronavirus SARS-CoV-2
TL;DR: This work is presenting a first-of-its-kind, designed multi-peptide subunit based epitope vaccine against COVID-19, made up of 33 highly antigenic epitopes from three proteins that have a prominent role in host receptor recognition, viral entry, and pathogenicity.
Journal ArticleDOI
Identification of potential inhibitors of Fasciola gigantica thioredoxin1: computational screening, molecular dynamics simulation, and binding free energy studies.
Rohit Shukla,Harish Shukla,Parismita Kalita,Amit Sonkar,Tripti Pandey,Dev Bukhsh Singh,Awanish Kumar,Timir Tripathi +7 more
TL;DR: A structure-based virtual screening of natural compounds from the ZINC database against the FgTrx1 structure found two compounds that could be potential drug candidates to fight against F. gigantica parasites.