P
Pascale Gerbaud
Researcher at French Institute of Health and Medical Research
Publications - 43
Citations - 1331
Pascale Gerbaud is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Trophoblast & Placenta. The author has an hindex of 21, co-authored 38 publications receiving 1161 citations. Previous affiliations of Pascale Gerbaud include Université Paris-Saclay & University of Paris.
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Journal ArticleDOI
Expression of HERV-W Env glycoprotein (syncytin) in the extravillous trophoblast of first trimester human placenta.
André Malassiné,Karen Handschuh,Vassilis Tsatsaris,Pascale Gerbaud,Valérie Cheynet,Guy Oriol,François Mallet,D. Evain-Brion +7 more
TL;DR: HERV-W Env glycoprotein expressed in villous and extravillous trophoblast can be considered as a specific marker of the human trophOBlast.
Journal ArticleDOI
Hyperglycosylated hCG is a marker of early human trophoblast invasion.
Jean Guibourdenche,Karen Handschuh,Karen Handschuh,Vassilis Tsatsaris,Pascale Gerbaud,Pascale Gerbaud,M. C. Leguy,M. C. Leguy,Françoise Muller,D Evain Brion,D Evain Brion,Thierry Fournier +11 more
TL;DR: This study suggests that the high levels of hCG-H observed in first-trimester maternal sera are mainly from invasive evct origin, reflecting the early trophoblast invasion process.
Journal ArticleDOI
Review: An overview of molecular events occurring in human trophoblast fusion.
TL;DR: The role of certain fusogenic protein macrocomplexes that form the scaffold for the fusogen machinery underlying human trophoblastic-lipid mixing and merging of cell contents that lead to cell fusion in physiological conditions are described.
Journal ArticleDOI
Increased oxidative damage to fibroblasts in skin with and without lesions in psoriasis.
Stéphanie Dimon-Gadal,Pascale Gerbaud,Patrice Thérond,Jean Guibourdenche,Wayne B. Anderson,Danièle Evain-Brion,Françoise Raynaud +6 more
TL;DR: It is found that there was more oxidative damage in cultured fibroblasts prepared from skin with and without lesions from psoriasis patients than in normal fibro Blasts from the skin of age-matched controls, and this damage is independent of any inflammatory infiltrate.
Journal ArticleDOI
Comparative Methylation of ERVWE1/Syncytin-1 and Other Human Endogenous Retrovirus LTRs in Placenta Tissues
Juliette Gimenez,Cécile Montgiraud,Cécile Montgiraud,Guy Oriol,Guy Oriol,Jean-Philippe Pichon,Karine Ruel,Vassilis Tsatsaris,Vassilis Tsatsaris,Pascale Gerbaud,Pascale Gerbaud,Jean-Louis Frendo,Jean-Louis Frendo,Danièle Evain-Brion,Danièle Evain-Brion,François Mallet,François Mallet +16 more
TL;DR: Results suggest that ERVWE1 and ERV3 could be developmentally epigenetically regulated HERVs, and might not be family related but copy-specific, and related to the LTR function and the tissue.