T
Thierry Fournier
Researcher at University of Paris
Publications - 166
Citations - 5560
Thierry Fournier is an academic researcher from University of Paris. The author has contributed to research in topics: Trophoblast & Placenta. The author has an hindex of 36, co-authored 158 publications receiving 4857 citations. Previous affiliations of Thierry Fournier include French Institute of Health and Medical Research & Centre national de la recherche scientifique.
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Journal ArticleDOI
Alpha-1-acid glycoprotein.
TL;DR: The use of AGP transgenic animals enabled to address in vivo, functionality of responsive elements and tissue specificity, as well as the effects of drugs that bind to AGP and will be an useful tool to determine the physiological role ofAGP.
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Diesel exhaust particles are taken up by human airway epithelial cells in vitro and alter cytokine production.
Sonja Boland,Armelle Baeza-Squiban,Thierry Fournier,Odile Houcine,Marie-Claude Gendron,M. Chevrier,Gilles Jouvenot,André Coste,Michel Aubier,Francelyne Marano +9 more
TL;DR: The results suggest that DEPs could 1) be phagocytosed by airway epithelial cells and 2) induce a specific inflammatory response.
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Placenta-specific Methylation of the Vitamin D 24-Hydroxylase Gene IMPLICATIONS FOR FEEDBACK AUTOREGULATION OF ACTIVE VITAMIN D LEVELS AT THE FETOMATERNAL INTERFACE
Boris Novakovic,Mandy Sibson,Hong Kiat Ng,Hong Kiat Ng,Ursula Manuelpillai,Vardhman K. Rakyan,Thomas A. Down,Stephan Beck,Thierry Fournier,D. Evain-Brion,Eva Dimitriadis,Jeffrey M. Craig,Jeffrey M. Craig,Ruth Morley,Ruth Morley,Richard Saffery,Richard Saffery +16 more
TL;DR: It is strongly suggested that epigenetic decoupling of vitamin D feedback catabolism plays an important role in maximizing active vitamin D bioavailability at the fetomaternal interface.
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Human chorionic gonadotropin produced by the invasive trophoblast but not the villous trophoblast promotes cell invasion and is down-regulated by peroxisome proliferator-activated receptor-gamma
Karen Handschuh,Jean Guibourdenche,Jean Guibourdenche,Vassilis Tsatsaris,Vassilis Tsatsaris,Mickaël Guesnon,Mickaël Guesnon,Ingrid Laurendeau,Danièle Evain-Brion,Danièle Evain-Brion,Thierry Fournier,Thierry Fournier +11 more
TL;DR: The results offer the first evidence that hCG secreted by the invasive trophoblast, likely the hyperglycosylated form of hCG, but not by the syncytiotrophobine, promotes trophOBlast invasion and may be a PPARgamma target gene in trophoplast invasion process.
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Review: hCGs: different sources of production, different glycoforms and functions.
TL;DR: HCG is the major pregnancy glycoprotein hormone, whose maternal concentration and glycan structure change all along pregnancy, depending on its source of production, glycoforms of hCG display different biological activities and functions that are essential for pregnancy outcome.