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Patricia A. Cleary
Researcher at National Institutes of Health
Publications - 13
Citations - 22558
Patricia A. Cleary is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Diabetes mellitus & Type 1 diabetes. The author has an hindex of 11, co-authored 12 publications receiving 21475 citations. Previous affiliations of Patricia A. Cleary include University of Washington & Harvard University.
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Journal ArticleDOI
The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus.
Diabetes Control,David M. Nathan,Saul M. Genuth,John M. Lachin,Patricia A. Cleary,O Crofford,Matthew M. Davis,Larry Rand,Carolyn Siebert +8 more
TL;DR: Intensive therapy effectively delays the onset and slows the progression of diabetic retinopathy, nephropathy, and neuropathy in patients with IDDM.
Journal ArticleDOI
Epidemiology of Diabetes Interventions and Complications (EDIC): Design, implementation, and preliminary results of a long-term follow-up of the Diabetes Control and Complications Trial cohort
H. Shamoon,Patricia A. Cleary,Annette Barnie,Saul M. Genuth,C. Maffin,William V. Tamborlane,J. Wesche,David M. Nathan +7 more
TL;DR: The participants, compared with nonparticipants, tended to have better glycemic control at the completion of the D CCT and were more likely to have their diabetes care provided by DCCT personnel and the quality of EDIC data is very similar to that observed in the DCCt.
Journal ArticleDOI
The effect of intensive glycemic treatment on coronary artery calcification in type 1 diabetic participants of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study
Patricia A. Cleary,Trevor J. Orchard,Saul Genuth,Nathan D. Wong,Robert Detrano,Jye Yu C. Backlund,Bernard Zinman,Alan M. Jacobson,Wanjie Sun,John M. Lachin,David M. Nathan +10 more
TL;DR: Waist-to-hip ratio, smoking, hypertension, and hypercholesterolemia, before or at the time of CT, were significantly associated with CAC in univariate and multivariate analyses and CAC was associated with mean HbA1c levels before enrollment, during the DCCT, and during the EDIC study.
Journal ArticleDOI
Glomerular filtration rate measurements in clinical trials
Andrew S. Levey,Andrew S. Levey,Tom Greene,Mark D. Schluchter,Patricia A. Cleary,Paul E. Teschan,Rodney A. Lorenz,Mark E. Molitch,William E. Mitch,Carolyn Siebert,Phillip M. Hall,Michael W. Steffes +11 more
TL;DR: The utility and precision of GFR measurements in multicenter trials, analyzed in 2,250 patients enrolled in 44 clinical centers participating in either the Modification of Diet in Renal Disease (MDRD) Study or the Diabetes Control and Complications Trial (DCCT), was excellent.
Intensive Diabetes Treatment and Cardiovascular Disease in Patients with Type 1 Diabetes The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study Research Group*
Patricia A. Cleary,Jye-Yu C. Backlund,Saul M. Ge,John M. Lachin,Philip Raskin,Bernard Zinman +5 more
TL;DR: In this article, the use of intensive therapy as compared with conventional therapy during the Diabetes Control and Complications Trial (DCCT) affected the long-term incidence of cardiovascular disease.