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Wanjie Sun

Researcher at George Washington University

Publications -  35
Citations -  3790

Wanjie Sun is an academic researcher from George Washington University. The author has contributed to research in topics: Type 1 diabetes & Diabetes mellitus. The author has an hindex of 25, co-authored 34 publications receiving 3381 citations. Previous affiliations of Wanjie Sun include Case Western Reserve University.

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Journal ArticleDOI

Intensive diabetes therapy and glomerular filtration rate in type 1 diabetes

TL;DR: The long-term risk of an impaired GFR was significantly lower among persons treated early in the course of type 1 diabetes with intensive diabetes therapy than among those treated with conventional diabetes therapy.
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Glycation and carboxymethyllysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the diabetes control and complications trial and epidemiology of diabetes interventions and complications participants with type 1 diabetes.

TL;DR: The role of glycation of proteins and AGE formation in the pathogenesis of retinopathy and nephropathy is strengthened and may explain the risk of these complications associated with prior A1C and provide a rational basis for the phenomenon of "metabolic memory" in the Pathogenesis of these diabetes complications.
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Prolonged effect of intensive therapy on the risk of retinopathy complications in patients with type 1 diabetes mellitus: 10 years after the diabetes control and complications trial

Neil H. White, +324 more
TL;DR: The persistent difference in diabetic retinopathy between former intensive and conventional therapy ("metabolic memory") continues for at least 10 years but may be waning.