T
Trevor J. Orchard
Researcher at University of Pittsburgh
Publications - 533
Citations - 46351
Trevor J. Orchard is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Diabetes mellitus & Type 1 diabetes. The author has an hindex of 96, co-authored 509 publications receiving 41593 citations. Previous affiliations of Trevor J. Orchard include University of Nottingham & Utrecht University.
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Journal ArticleDOI
Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes.
David M. Nathan,Patricia A. Cleary,Jye Yu C. Backlund,Saul Genuth,John M. Lachin,Trevor J. Orchard,Philip Raskin,Bernard Zinman +7 more
TL;DR: Intensive diabetes therapy has long-term beneficial effects on the risk of cardiovascular disease in patients with type 1 diabetes, and changes between treatment groups remained significant after adjusting for these factors.
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Global Prevalence and Major Risk Factors of Diabetic Retinopathy
Joanne W.Y. Yau,Sophie Rogers,Ryo Kawasaki,Ecosse L. Lamoureux,Ecosse L. Lamoureux,Jonathan W. Kowalski,Toke Bek,Shih-Jen Chen,Jacqueline M. Dekker,Astrid E. Fletcher,Jakob Grauslund,Steven M. Haffner,Richard F. Hamman,M. Kamran Ikram,Takamasa Kayama,Barbara E. K. Klein,Ronald Klein,Sannapaneni Krishnaiah,Korapat Mayurasakorn,J. P. O'Hare,Trevor J. Orchard,Massimo Porta,Mohan Rema,Monique S. Roy,Tarun Sharma,Jonathan E. Shaw,Hugh R. Taylor,James M. Tielsch,Rohit Varma,Jie Jin Wang,Ningli Wang,Sheila K. West,Liang Xu,Miho Yasuda,Xinzhi Zhang,Paul Mitchell,Tien Yin Wong,Tien Yin Wong,Tien Yin Wong +38 more
TL;DR: Longer diabetes duration and poorer glycemic and blood pressure control are strongly associated with DR, and these data highlight the substantial worldwide public health burden of DR and the importance of modifiable risk factors in its occurrence.
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A randomized trial of therapies for type 2 diabetes and coronary artery disease.
L. Frye,Phyllis August,Regina M. Hardi,Sheryl F. Kelsey,Trevor J. Orchard,Bernard R. Chaitman +5 more
TL;DR: Overall, there was no significant difference in the rates of death and major cardiovascular events between patients undergoing prompt revascularization and those undergoing medical therapy or between strategies of insulin sensitization and insulin provision.
Journal ArticleDOI
Global prevalence and major risk factors of diabetic retinopathy.
Olubukola Ajala,Patrick English,Jonathan Pinkney,Joanne W.Y. Yau,Sophie Rogers,Ryo Kawasaki,Ecosse L. Lamoureux,Jonathan W. Kowalski,Toke Bek,Shih-Jen Chen,Jacqueline M. Dekker,Astrid E. Fletcher,Jakob Grauslund,Steven M. Haffner,Richard F. Hamman,M. Kamran Ikram,Takamasa Kayama,Barbara E. K. Klein,Ronald Klein,Sannapaneni Krishnaiah,Korapat Mayurasakorn,J. P. O'Hare,Trevor J. Orchard,Massimo Porta,Mohan Rema,Monique S. Roy,Tarun Sharma,Jonathan E. Shaw,Hugh R. Taylor,James M. Tielsch,Rohit Varma,Jie Jin Wang,Ningli Wang,Sheila K. West,Liang Xu,Miho Yasuda,Xinzhi Zhang,Paul Mitchell,Tien Yin Wong +38 more
TL;DR: The Meta-Analysis for Eye Disease (META-EYE) Study Group’s Global Prevalence and Major Risk Factors of Diabetic Retinopathy and Diabetes care, 35 (3).
Journal ArticleDOI
The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the Diabetes Prevention Program randomized trial.
Trevor J. Orchard,Marinella Temprosa,Ronald B. Goldberg,Steven M. Haffner,Robert E. Ratner,Santica Marcovina,Sarah E. Fowler +6 more
TL;DR: In this paper, the authors used lifestyle intervention and metformin therapy to reduce the incidence of metabolic syndrome in the participants of the Diabetes Prevention Program. But, only half of the participants had the metabolic syndrome.