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Patricia Cristina Lisboa

Researcher at Rio de Janeiro State University

Publications -  202
Citations -  4362

Patricia Cristina Lisboa is an academic researcher from Rio de Janeiro State University. The author has contributed to research in topics: Offspring & Leptin. The author has an hindex of 36, co-authored 188 publications receiving 3819 citations. Previous affiliations of Patricia Cristina Lisboa include Ponta Grossa State University & Federal University of Rio de Janeiro.

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Maternal high-fat diet induces obesity and adrenal and thyroid dysfunction in male rat offspring at weaning.

TL;DR: Maternal high‐fat diet increased adrenal catecholamines in offspring but reduced liver and adipose tissue adrenoreceptors, thereby contributing to increased adiposity in these animals and contributing to the development of hypertension.
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Neonatal leptin treatment programmes leptin hypothalamic resistance and intermediary metabolic parameters in adult rats.

TL;DR: It is concluded that neonatal leptin treatment programmes both hyperleptinaemia and hyperinsulinaemia in adulthood, which leads to leptin resistance by reducing the expression of the hypothalamic leptin receptor.
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Neonatal Programming of Neuroimmunomodulation – Role of Adipocytokines and Neuropeptides

TL;DR: The programming effects of these hormones upon body weight, body composition, insulin action, thyroid, adrenal and immune and inflammatory responses, with special emphasis on leptin, a cytokine that seems to play a central role in these events.
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Postnatal early overnutrition changes the leptin signalling pathway in the hypothalamic-pituitary-thyroid axis of young and adult rats.

TL;DR: It is shown that postnatal EO induces short‐ and long‐term effects upon the hypothalamic–pituitary–thyroid axis, which may help to explain future development of metabolic and endocrine dysfunctions, such as metabolic syndrome and hypothyroidism.